莫菲特癌症中心(Moffitt Cancer Center)的研究人员发现了一种通过靶向一种名为巨噬细胞受体MARCO(macrophage receptor with collagenous structure)的蛋白质来增强癌症免疫疗法的新方法。他们的研究发表在《Journal for ImmunoTherapy of Cancer》上,显示在黑色素瘤(最致命的皮肤癌形式)中,将MARCO阻断与一种名为抗CTLA4疗法...
MARCO (macrophage receptor with collagenous structure) belongs to the class A scavenger receptor molecules. The structure and function of the molecule is described. Although it is expressed on subsets of macrophages, it can be upregulated on other macrophages after bacterial infection. The strategic ...
上海泽叶生物科技有限公司 VIP6年 联系人:宛双凤 电话:021-61998551拨打 手机:13122364865 拨打 邮箱:sale1@shzysw.net 产品详情:中文名称: 胶原结构巨噬细胞受体(MARCO)重组蛋白 英文名称: Recombinant Macrophage Receptor With Collagenous Structure (MARCO)...
MARCO (macrophage receptor with collagenous structure), also known as SCARA2, is an 80 kDa type II transmembrane glycoprotein in the class A scavenger receptor family (1). Human MARCO consists of a 43 aa cytoplasmic domain, a 21 aa transmembrane segment, and a 456 aa extracellular domain (EC...
Macrophage receptor with collagenous structure (MARCO) is a member of the class A scavenger receptor family which is expressed on the cell surface of macrophages. It is well known that MARCO avidly binds to unopsonized pathogens, leading to its ingestion by macrophages. However, the role of ...
关键字:MARCO;Macrophage receptor;Marco;Macrophage receptor ;SCARA2;Scavenger ;Scavenger receptor c;MARCO_HUMAN; 公司简介 上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品:试剂盒,ELISA试剂盒,抗体,重组蛋白,血清,胎牛血清,细胞,原代细胞 细胞培养试剂,常用生化试...
MARCO 导读 基因简介 中英文全称:巨噬细胞受体含成胶结构 macrophage receptor with collagenous structure 分布:细胞质|融入质膜|膜 活性:清除 因子受体|模式识别受体 参与:磷酸运输|细胞表面受体连 接信号转导|应答病原细菌 OMIM/位置:604870 2q12-q13
MARCO (macrophage receptor with collagenous structure), also known as SCARA2, is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family (1). Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449...
Among various surface receptors that activate the macrophages to phagocytize particles, it is believed that the Toll‐like receptor 4 (TLR4) and the scavenger macrophage receptor with collagenous structure (MARCO) play key roles in recognition of wear debris particles. However, a strong body of ...
英文名称:Polyclonal Antibody to Macrophage Receptor With Collagenous Structure (MARCO)货号PAC614Po01 物种Sus scrofa; Porcine (Pig) 实验方法Western blotting: 0.5-2µg/mL;Immunohistochemistry: 5-20µg/mL;Immunocytochemistry: 5-20µg/mL;Optimal working dilutions must be determined by end user...