Bertoni F, Ghielmini M, Cavalli F et al. Mantle cell lymphoma: new treatments targeted to the biology. Clin Lymphoma 2002; 3: 90- 96.Ghielmini M, Cavalli F et al. Mantle cell lymphoma: new treatments targeted to the biology. Clin Lymphoma 2002; 3: 90–96 - Bertoni () Citation ...
The global mantle cell lymphoma treatment market is projected to grow at a rapid pace in the next few years due to rise in the number of people suffering from mantle cell lymphoma and increase in research and development activities in the hea...
Mantle cell lymphoma (MCL) predominantly affects older adults, with a median age at diagnosis of 70 years. A frequently aggressive yet incurable lymphoma, the goal of therapy for MCL is to turn a potentially life-threatening illness into a chronic disease with prolonged periods of remission. Larg...
套细胞淋巴瘤(mantle cell lymphoma,MCL)的预后分层 MCL兼具侵袭性淋巴瘤进展迅速和惰性淋巴瘤不可治愈的双重特点,大多数有很强侵袭性,难以治愈,不同治疗方案的中位生存期约3-5年。近年来的临床研究显示,套细胞淋巴瘤也是一组异质性肿瘤,预后差异很大...
Mantle cell lymphoma (MCL) is an aggressive form of B cell non-Hodgkin's lymphoma and remains incurable under current treatment modalities. One of the main reasons for treatment failure is the development of drug resistance. Accumulating evidence suggests that B cell activating factor (BAFF) and ...
Mantle cell lymphoma (MCL) is an uncommon, incurable B-cell non-Hodgkin's lymphoma that afflicts the elderly. There is no standard course of treatment, wit... T Tang,P Martin - 《Current Hematologic Malignancy Reports》 被引量: 0发表: 2014年 Mantle cell lymphoma: advances in biology and...
套细胞淋巴瘤(mantle cell lymphoma, MCL)是一种不常见的血液系统恶性肿瘤,占非霍奇金淋巴瘤7%。其特征是t(11;14)(q13;q32)移位,导致过度表达细胞周期素D1。绝大多数病例的免疫组化染色可以发现Cyclin D1和CD5阳性。少部分Cyclin D1阴性的患者常有SOX-11表达阳性。套细胞淋巴瘤仍然是一群异质性很强的疾病,...
Mantle cell lymphoma is an aggressive non-Hodgkin’s lymphoma that remains incurable with current chemotherapeutic approaches. Despite response rates to many regimens of 50% to 70%, the disease typically progresses after chemotherapy with a median survival time of approximately 3 years. There is no ...
Mantle cell lymphoma is a malignant disease in which intensive treatment can prolong life. In a new study, scientists from Uppsala University and other Swedish universities show that people with mantle cell lymphoma who were unmarried, and those who had low educational attainment, were less often ...
Several key modifications of the therapeutic algorithm of mantle cell lymphoma treatment implemented in the past 10 years resulted in significantly improved prognosis of patients. The milestones in the therapy of mantle cell lymphoma include incorporation of anti-CD20 monoclonal antibody rituximab into ...