Macrophage response to peripheral nerve injury: the quantitative contribution of resident and hematogenous macrophages. Lab Invest 2003; 83(2): 175-85.MuellerM,LeonhardC,WackerK,etc.Macrophageresponsetoperipheralnerveinjury:thequantitativecontributionofresidentandhematogenousmacrophages.[J].2003,2(2)....
For treating wound repair disorders more should be elucidated on the role of macrophages in these conditions, especially their functional phenotype, to find more therapeutic opportunities. This review summarizes macrophage function in skin injury repair, thereby providing more insight in macrophage function...
A better understanding of the role of Hsp in MΦ function may provide new directions in the development of therapeutic approaches for the treatment of inflammation, injury and other immune diseases. In this review, we attempt to provide an overview of the role of Hsp on MΦ. function and ...
a) Following injury, tissue-resident macrophage populations function as sentinels and become rapidly activated and contribute to a pro-inflammatory environment within the wound. During the “Coagulation and Inflammation” phase, this pro-inflammatory environment induces the influx of the first wave of ...
Sialylated IgG protects against severe influenza by inducing the transcriptional repressor REST, which dampens the inflammatory response and preserves lung tissue function. Lucy Bird Research Highlights29 Nov 2024Nature Reviews Immunology Volume: 25, P: 2 ...
A third population of human monocytes expressing both CD14 and CD16 has been shown to comprise at least 2 subpopulations with distinct capacities to release TNF-α and IL-1 in response to lipopolysaccharide. The function of these CD14+CD16+ cells remains unclear, but their frequency in the ...
Seven days after left coronary artery ligation, GRLysMCremice exhibited worse cardiac function and adverse remodeling associated with impaired scar formation and angiogenic response to ischemic injury. Inactivation of GR altered the functional differentiation/maturation of monocyte-derived macrophages in the ...
The effect of molecular weight and β-1,6-linkages on priming of macrophage function in mice by (1,3)-β-d-glucan 1,3-β-D-glucans (glucans) are structural elements in the cell walls of yeast and fungi with immunomodulatory properties, mediated through their ability to... Janelle,A,Clea...
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We demonstrate that after injury, including in humans, macrophages function to clear debris and persist within the nerve microenvironment. Macrophage ablation immediately preceding remyelination results in an increase in immature Schwann cell density, a reduction in remyelination, and long-term deficits ...