increases.1For patients with ≤4 cm2accessible defects of the knee, early diagnosis and treatment may minimize lesion progression and the need for open ACI.1If conservative treatment has not worked to relieve pain associated with knee cartilage damage, MACI may be an appropriate treatment option....
MACI is contraindicated in patients with a known history of hypersensitivity to gentamicin, other aminoglycosides, or products of porcine or bovine origin. MACI is also contraindicated for patients with severe osteoarthritis of the knee, inflammatory arthritis, inflammatory joint disease, or uncorrected ...