Lrrc10 is a novel cardiac- specific target gene of Nkx2-5 and GATA4. J Mol Cell Cardiol 2013; 62: 237-46.Brody MJ, Cho E, Mysliwiec MR, Kim TG, Carlson CD, Lee KH, Lee Y. 2013. Lrrc10 is a novel cardiac-specific target gene of Nkx2-5 and GATA4. J Mol Cell Cardiol 62...
[6] Brody MJ,Hacker TA,Patel JR,et al.Ablation of the cardiac- specific gene leucine-rich repeat containing 10(Lrrc10)results in dilated cardiomyopathy[J].PLoS One,2012,7(12):e51621. [7] Elliott P,O′Mahony C,Syrris P,et al.Prevalence of desmosomal protein gene mutations in patients...
The gene that encodes LRRC10 maps to human chromosome 12q15 and murine chromosome 10 D2. Also known as: HRLRRP; leucine-rich repeat-containing protein 10;Anti-LRRC10抗体 Leucine-rich repeat-containing protein 10 Gene names; Leucine-rich repeat-containing protein 10 Gene names; LRRC10A;...
Ensembl Gene ID ENSMUSG00000060187.5 Ensembl mRNA ID Lrrc10-201 包装清单: 产品编号 产品名称 包装 QM61738S Mouse Lrrc10 qPCR Primer Pair 1nmol each — 说明书 1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有...
Sudden cardiac deathGeneticsLeucine-rich repeat containing 10 (LRRC10) geneSudden unexplained nocturnal death syndrome (SUNDS) is a perplexing disorder to both forensic pathologists and clinic physicians. Clinical features of SUNDS survivors suggested that SUNDS is similar to Brugada syndrome (BrS). ...
(SRF) by a yeast two-hybrid method;(2) screening candidate genes for reducing expression at a heart by using a myocardial hypertrophy model, and analyzing to obtain an Lrrc10 gene which is expressed in the heart specially; and (3) taking the Lrrc10 gene as candidate gene molecules to ...
Gene expression profiling of embryonic Lrrc10-/- hearts identified pathways and transcripts involved in regulation of the actin cytoskeleton to be significantly upregulated, implicating dysregulation of the actin cytoskeleton as an early defective molecular signal in the absence of LRRC10. In contrast,...