Because early administration of intensive chemotherapy for LARC has more advantages than adjuvant chemotherapy, total neoadjuvant therapy (TNT) has been introduced and evaluated to determine whether it can improve tumor response or treatment outcomes. This study aims to investigate whether short-course ...
Adjuvant chemotherapy According to the Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines for the treatment of colorectal cancer [26], for postoperative Stage III patients, adjuvant chemotherapy was recommended (either CapOx: oxaliplatin + capecitabine or FOLFOX: fluorouracil ...
Marco MR, Zhou L, Patil S, et al; Timing of Rectal Cancer Response to Chemoradiation Consortium. Consolidation FOLFOX6 chemotherapy after chemoradiotherapy improves survival in patients with locally advanced rectal cancer: final results of a multicenter phase II trial. Dis Colon Rectu...
(CheckMate-227)Median duration of overall survival Opdivo + Yervoy: 17.1 months (95% CI 15.0-20.1) vs Chemotherapy: 14.9 months (95% CI 12.7-16.7) Overall survival rate Opdivo: 40% at 2 years vs Chemotherapy: 32.8% Non-small cell lung cancer- first-line treatment of metastatic or recurren...
survival in terms of prognostic factors (initial treatment, age, sex, location, stage, number of lymph nodes resected, and adjuvant chemotherapy). The location was divided into left and right side, and the cutoff value for the number of lymph nodes was set up to 25. All P values were ...
Abdominal computed tomography (CT) was performed every 4 to 6 months, and the pa- tients were prescribed adjuvant chemotherapy, such as FOLFOX, FOLFIRI, or CAPEOX, even after a curative (R0) resection. The assessments described above were repeated every month. Statistical analysis Overall ...
Furthermore, mounting evidence suggests that dysregulated lncRNAs are intricately associated with the development of chemoresistance in various types of cancers [11]. In recent decades, significant advancements have been made in chemotherapy regimens and the management of drug side effects for the ...
In spite of the two metachronous aggressive cancers, this patient is achieving long term survival due to the combination of anti EGFR and chemotherapy.The insignificant infrequency of this case prompted us to perform a molecular characterization of both neoplasms with the aim to investigate the ...