Prospective data on prevalence of oxaliplatin induced acute and long-term neuropathy in a real-life patient population and its effects on quality of life (QOL) and survival is limited, and scarce in CAPOX versus FOLFOX treated, especially in a subarctic climate. Methods: One hundred forty-four ...
We additionally investigated the consistency of long-term results with our earlier findings and analyzed the 5-year OS and progression free survival (PFS). We also summarized the late adverse events and post-relapse treatments of some patients, which provides a reference for clinicians....
Therefore, the effects of preRT on the long-term survival benefits deserves to be re-evaluated. This study analyzed patients from the SEER database diagnosed between 2011 and 2015 to re-evaluate the clinical value of preRT in the TME era and identify candidates who may benefit from preRT ...
After consideration of the long-term side effects elicited by radiotherapy, several studies have endeavored to explore the role of neoadjuvant chemotherapy (nCT) as monotherapy. In the FOWARC study, though the neoadjuvant with mFOLFOX6 alone achieved a postoperative pCR rate of 6.6%, the rates of...
The prognosis for patients with liver metastases from gastric cancer is very poor and the 5-year overall survival rate of synchronous liver metastases from gastric cancer was less than 27% [[1], [2], [3]]. Some scholars reported GCLM patients with long-term survival, but no one live for...
This cohort study investigates the association of delayed surgery with oncologic long-term outcomes in patients with nonresponsive locally advanced rectal
duration and effects of preoperative treatment, the surgical procedure, the timing, location and treatment of recurrence, as well as the post-operative and long-term outcome. Data are regularly updated by each centre, and a quality control of the data is performed by a data manager who sends ...
we always recommend that elective surgery should be performed within 2 weeks after the SEMS insertion. In real-world clinical cases, various cases were included. Large-scale, randomized controlled trials are desirable to clarify the oncological long-term effects of colonic SEMS as a BTS in the ...
Almost irrespective of the cost figures themselves, the exercise of estimating ‘total’ cost associated with the long-term effects of therapy allows for a thoughtful examination of a range of clinical, lifestyle, financial, social, and temporal elements that extend well beyond the scope of the ...
Thomas J. George, MD, FACP, highlights the long-term data from the NRG-GI002 trial, the next steps for exploring subsets of patients who may benefit from the addition of pembrolizumab or veliparib to total neoadjuvant therapy, and what the use of total n