Jan F.C.Glatz, ...Joost J.F.P.Luiken, inBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2020 5.4Lipotoxicity and glucotoxicity A predominant ATP production from either fatty acids or glucose renders the heart at risk for so-calledlipotoxicityandglucotoxicity, respectively.Li...
Doxorubicin Hydrochloride IP 2 mg (as pegylated liposomal) Water for Injection IP q.s. Lipodoxis provided as a sterile, transluscent, red dispersion in single use vials. Storage & Handling Store at 2°C-8°C. Do not freeze. Expiry Date Refer product label for expiry date. Do not use ...
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Thus, liposomes can act as vectors able to carry anticancer agents for preferential delivery to distal tumor sites following intravenous injection [5], [6], [7], although some controversy exists on the advantage of lipoplexes with respect to viral vectors in gene therapy protocols [8]. The ...
37 °C. Oligomycin (1 μM; ATP synthase inhibitor) was injected following basal OCR measurements followed by injection of FCCP (1 μM; an uncoupling agent that collapses the proton gradient and disrupts the mitochondrial membrane potential), and finally by injection of a mixture of ...
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(1.5–5 µg/mL) for 84 s, each followed by injection of running buffer for 600 s. The surfaces were regenerated after each cycle using one 30-s pulse injection of 10 mM glycine, pH 1.2, 0.5 M NaCl, and immediately re-equilibrated with running buffer. Data were collected...
injection of 0.4 ml of a 0.9% solution of NaCl containing 100 μg ovalbumin (OVA) adsorbed on 1.6 mg Al(OH)3 (all Sigma) the mice received a second dose of the same s.c. injection. On day 11 Peritonitis was induced by the intraperitoneal (i.p.) injection of 0.4 ml of a ...