For lipid replication, 69,635 participants from the Nord-Trøndelag Health (HUNT) study and 390,606 participants of the UK Biobank with genome-wide array data and lipid data were included. The HUNT study is a longitudinal, repetitive population-based health survey conducted in the county of No...
it cannot be inferred from simple observational studies which of these associated lipid species have causal effect on CVDs. Nonetheless, genomics provides an alternative approach to infer causality using the intrinsic properties of the genome, i.e., the random ...
After adjusting for equivalent levels of immunoprecipitated ARID3A inputs (Figure 4B, middle panel), WT and mutant lysates were fractionated on SDS-PAGE and then Western blotted with an EZRIN monoclonal antibody (mAb). As shown in Figure 4B, EZRIN–ARID3A interaction was abrogated only by ...