lichen sclerosusvulvavulvar lichen sclerosusLichen sclerosus is a non-neoplastic chronic inflammatory dermatosis that can affect any cutaneous body surface, showing particular predilection for the anogenital area in females. It is clinically characterized by progressive and worsening degeneration of the dermal...
In females, the vulva and anus In males foreskin of the penis Non-genital areas involve hair follicles or sweat glands on the surface of skin, breasts, and underarms. Signs and symptoms of Lichen Sclerosus: If the disease is a mild case, there may be no symptoms. ...
Vulvar lichen sclerosus (LS) is a chronic skin condition that affects the vulva (the skin surrounding the opening of the vagina) and anus and is followed by itching and pain. Facts This condition can occur in people of any age, including children, females of reproductive age, and adults ...
Lichen sclerosus et atrophicusis the final lesion to differentiate from oral lichen planus. Extremely rare in the mouth, this typically genital mucositis may be clinically indistinguishable from oral lichen planus. The epithelium is uniformly atrophic, often extremely so, and only a thin layer of su...
Background Lichen sclerosus et atrophicus (LSEA) is a chronic inflammatory dermatosis of genital and extragenital sites with a prevalence ranging from 9% in prepubertal patients to 50% in postmenopausal patients. Chat generative pre-trained transformer (ChatGPT) is an artificial intelligence tool des...
Fifty Caucasian females with lichen sclerosus et atrophicus were investigated to determine their HLA types. HLA-B40 was the only antigen found to be significantly more common in these patients when compared with a control population.doi:10.1111/j.1365-2133.1981.tb08171.x...
patients (3 males and 3 females) with histologically proven lichen sclerosus that showed relative sparing of the uncovered areas of the genitals, thereby suggesting that the occlusion of the genital skin may be playing a greater role in the causation of LS than is currently thought, in both ...
Lichen sclerosus et atrophicus (LSA) is an uncommon disease of the skin and mucosae of either sex. Apart from a number of complications, SCC developing from a lesion of LSA in males is rare, although it is well known in females. We report two cases recently seen by us to alert ...
Is it necessary to continue treatment for patients with lichen sclerosus who do not have any symptoms and/or signs of disease activity? What is the impact on quality of life? Does the disease course of lichen sclerosus differ in boys and girls, adult males and females?
lichen sclerosussusceptibilityLichen sclerosus (LS) is considered to have an immunogenetic background. Several small studies, using serological typing, have reported that HLA-DR11, DR12, and DQ7 were increased in LS, with DR17 less frequent. This study aimed to validate and detect new HLA-DR ...