lymphocyticinflammatory infiltrateis present. Colloid bodies may form from degeneratedkeratinocytes. Several investigators have reported an association of lichen planus with vulvar cancer[32,33]. Although the exact risk ofmalignancyis not known, their coexistence with lichen sclerosis suggests a similar ...
Cases were categorized either as LS or vestibulovaginal sclerosis based on presence or absence of basal layer degeneration and lymphocytic infiltrate. Clinical data collected included examination findings, biopsy site and indication, previous vulvovaginal surgery, medications at time of biopsy, vulvar LS...
(in R11 beta = 0.79, p = 6.5 × 10−142) and other inflammatory diseases such as ankylosing spondylitis, psoriasis, and iridocyclitis,37 but with a significant opposite-direction protective effect in canonical autoimmune diseases such as hypothyroidism, type 1 diabetes, and multiple sclerosis....
Lichen planus can display various lesion types, but the most common presentation is an area of polygon-shaped, itchy, violaceous, flat-topped papules a few millimeters wide. This classic presentation is known as the 6 Ps of lichen planus—purple, polygonal, planar, pruritic, papules, and plaq...
Significant improvement was maintained at the 12‐month follow‐up, with 89% of subjects showing at least one‐point improvement in elasticity compared to baseline; 86% in lichenification; 88% in sclerosis; and 80% in whitening and parchment‐like skin. Labial fusion and the extent of disease ...
lymphocyticinflammatory infiltrateis present. Colloid bodies may form from degeneratedkeratinocytes. Several investigators have reported an association of lichen planus with vulvar cancer[32,33]. Although the exact risk ofmalignancyis not known, their coexistence with lichen sclerosis suggests a similar ...
the infiltrate is often separated from the epithelium by a hyalinized band. Subepithelial hyalinization is also a feature of systemic sclerosis or scleroderma,amyloidosis, andoral submucous fibrosis. Congo red birefringence andthioflavin Tfluorescence can help to rule out amyloidosis, but differences in...