Mosquitoes serve as a vector of many diseases like malaria, dengue hemorrhagic fever (DHF), chikungunya, filariasis, Japanese encephalitis, and dengue shock syndrome (DSS) etc. Aedes aegypti and A. albopictus are major vectors of dengue fever. However, with only limited nu...
Aside from brain damage caused by serious infections like rubella or encephalitis, "there is growing awareness that a wider range of infections may have a more subtle and/or delayed impact on brain function," the researchers write. The study is the largest to date to analyze infections as a ...
Schuster indicated that there were no new findings regarding safety. The most common high-grade toxicities any time after infusion were neutropenia (43%) and anemia (19%), with frequent serious adverse effects (AEs) including cytokine release syndrome (CRS; 20%), pneumonia (11%), and febrile...
We previously reported that extracellular particles (EPs) composed of premembrane (prM) and envelope (E) proteins were released from cells infected with recombinant vaccinia viruses encoding Japanese encephalitis (JE) virus prM and E genes. In the present study, EPs were evaluated for induction of...
Some of these vaccines have faced similar challenges to influenza: malaria, Japanese encephalitis, meningitis A and dengue each have restricted geographical risk in mainly LMIC targets; pneumococcal vaccines require multiple, geographically specific serotypes; and Hib-vaccine developers faced challenges in ...
Horses were annually vaccinated against rabies, tetanus, West Nile Virus, Eastern and Western Encephalitis, and were regularly dewormed. Horses were clinically healthy throughout the studies. A summary of age, gender and vaccination groups of the horses in the four experimental vaccine trials is ...