Genome-wide association studies were undertaken in UK and Japanese populations. Stone forming individuals were identified from the UK Biobank using ICD-10 and OPCS codes and a single UK Biobank self-reported operation code for kidney stone surgery and excluded if recorded to have a disorder known ...
The mendelian randomization effect of genetic proxies of thiazide diuretics on kidney stones was estimated in the MVP, UKB, and FinnGen individually (eTables 6-9 in Supplement 1) and then combined in a random-effects meta-analysis (eTable 10 in Supplement 1). In the meta-analysis, genetic ...
Kidney stones ○ Hypertension ○ Renal cystsmay be discovered, even onprenatal ultrasound. • ARPKD ○ Parents unaffected ○ Respiratory distress ○ Oligohydramnios ○ Spontaneous pneumothoraces ○ Severe hypertension ○ Portal hypertensionwith age ...
The risk factors for kidney cancer have been categorized as: (a) life style risk factors—tobacco smoking, excess body weight, alcohol consumption, physical activity and diet; (b) medical history—hypertension, chronic kidney diseases, kidney stones, and diabetes mellitus; (c) environmental and ...
46–51 In contrast, CKD–MBD is difficult to define in clinical practice and does not have any specific ICD-9 (or soon, ICD-10) diagnostic code or known relationship to fracture risk. While it is known that the biochemical abnormalities accompanying CKD–MBD alter bone turnover or ...
(a local coding system that predates ICD-9 codes). On review of these code sets, we determined that 173 of these were conditions/diseases that if truly present, would always lead to exclusion as a donor. Of these exclusionary diseases, 26 were prevalent on or prior to the index date of...
dynamic bone turnover parameters, which have specific criteria for the specific type of renal osteodystrophy.46–51 In contrast, CKD–MBD is difficult to define in clinical practice and does not have any specific ICD-9 (or soon, ICD-10) diagnostic code or known relationship to fracture risk....
existing kidney stones were an exclusionary criteria for trial randomization. Serum uric acid did rise significantly more than placebo, though the clinical consequences of this change in serum uric acid over the trial duration are unknown. There are no data on the effect of teriparatide in subjects...
We assessed comorbidities and co-medications in the claims during the 12 months before the treatment initiation using ICD-9-CM diagnosis and procedure codes and 11-digits national drug codes (NDC), including: other kidney disease, proteinuria, kidney stones, hypercalciuria, diabetes mellitus, cardiova...
(e.g., cardiac arrhythmias, hyporeflexia, and muscle weakness). These are areas for future research. Furthermore, we employed ICD-10 code N20 to identify kidney stones, which includes but is not limited to calcium-based stones. However, since approximately 80% of kidney stones are calcium-...