A subset of patients with schizophrenia and DefSCZ experience physiosomatic symptoms reminiscent of chronic fatigue and fibromyalgia. However, there are no data whether, in DefSCZ, physiosomatic symptoms are associated with increased levels of cytokines/chemokines. This study examined the associations ...
The human KALRN gene, which encodes a complex, multifunctional Rho GDP/GTP exchange factor, has been linked to cardiovascular disease, psychiatric disorders and neurodegeneration. Examination of existing Kalrn knockout mouse models has focused only on ne
Mental health disorders (MHDs) encompass a wide range of conditions that affect mood, thinking, behavior, and emotional well-being [5]. Examples of MHDs include depression, anxiety disorders, post-traumatic stress disorder (PTSD), bipolar disorder, schizophrenia, and eating disorders. These ...
Depression has emerged as a significant global health concern, exerting a profound impact on individuals, as evidenced by its high prevalence and associated suicide rates. Considering its pervasive nature, the absence of optimal treatment modalities rema
Pursue partnership opportunities for the development of our pipeline About Brilaroxazine Brilaroxazine is an in-house discovered new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors implicated in schizophrenia and its comorbid symptoms. Positive topline data...
This journey begins with recognizing the signs of codependence within yourself. There are five primary symptoms of codependence you should look out for. Symptom #1: Unhealthy levels of self-esteem. Codependent people lack the healthy self-esteem that allows them to see themselves as valuable human...
A confidence score cut-off of 0.5 was selected to include enough nodes in the network, while maintaining a high selectivity [18]. Subsequently, the network was expanded to incorporate an additional 20 interactors based on their total connectivity to other proteins in the network relative to their...
(age ≥12 months) DDH had been included. Non-English reports were omitted if the abstract did not include adequate information become included for evaluation. The amount of newborns screened and the recognition prices had been extracted. Meta-analysis calculated the pooled incidenceof DDH per 1000...
The methods and the goals of psychosocial interventions used in the medically ill are often determined by the consideration of disease onset, etiology, course, prognosis, treatment, and understanding of the nature of the presenting psychiatric symptoms in addition to an understanding of the patient’...
of-interest (ROI) analyses, and if the thalamic or the cerebellar metabolism correlates with clinical features. In particular, since imaging studies in schizophrenia patients had shown a correlation of positive symptoms (i.e. hallucinations and delusions) with thalamic volumes15, we aimed to explore...