Then,2.5 grams of a 2% ketoconazole cream was applied to an area of 9 x 1 cm2at the center of the stripped area. Microdialysis was performed at 14/min flow rate and samples were collected every hour for 6 hours. In another attempt, an oral formulation of ketoconazole (200 mg) was ...
Fungal skin infections are currently a major clinical problem due to their increased occurrence and drug resistance. The treatment of fungal skin infections is based on monotherapy or polytherapy using the synergy of the therapeutic substances. Tea tree