This chemically modified electrode (CME) utilises a conducting polymer as the source of charge carrier and Vitamin-K as the water-insoluble redox species that bonds protons in reduction and releases protons in oxidation. The overall number of active proton bonding sites was found to be 1.36 脳 ...
Proton sensing in ROMK channels requires multiple sites or residues in the channel protein to interact with protons. A lysine residue (Lys-80 in ROMK1 or Lys-61 in ROMK2) in the N terminus of channel proteins plays a critical part in the channel sensitivity to intracellular pH. Mutation of...
Furthermore, we observed that mClC-K1 currents were still stimulated by external calcium and inhibited by protons in the absence of Barttin. Consequently, this must be an intrinsic property of the ClC-K, as has been reported elsewhere [12]. Barttin also modulates ClC-K gating [14]. Fahlke ...
[3] Joliot-Curie, Irène & Joliot, Frédéric (1932). "Émission de protons de grande vitesse par les substances hydrogénées sous l'influence des rayons γ très pénétrants" [Emission of high-speed protons by hydrogenated substances under...
A number of aspects of radiotherapy using protons and ions such as carbon and neon are discussed, focusing less on the oft-enumerated advantages or potenti... M Goitein - 《Radiotherapy & Oncology》 被引量: 159发表: 2009年 Trials and tribulations of 'omics data analysis: assessing quality ...
We report here on a new measurement of the parity-violating (PV) asymmetry in the scattering of polarized electrons on unpolarized protons performed at the... Maas,F.,E. - 《European Physical Journal A Hadrons & Nuclei》 被引量: 53发表: 2003年 ...
With primary protons of 15 lA at 50 GeV, K À intensity of 10 7 per spill will be deliv- ered to the experimental area. The maximum central momentum of the K1.8 beam line is 2 GeV/c, since the ele- mentary cross section of N À production via p(K À , K + ) reac- ...
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transport. The renal outer medullar K (ROMK1) channels show an exquisite sensitivity to intracellular protons (pHi) (effective pa approximately 6.8) and play a key role in K homeostasis during metabolic acidosis. Our molecular dynamic simulation results suggest that PKC-mediated phosphorylation on ...
Importance of arginine-188 in the interaction; Inhibition of intracellular protons; Regulation of ROMK channels by multiple signaling pathways.Wei-ZhongZengHorng-HueiLiouKrishnaU.MuraliFalckJ.R.Chou-LongAmerican Journal of Physiology: Renal Physiology...