In DM2 (or proximal myotonic myopathy [PROMM]), the genetic defect consists of a CCTG repeat expansion (75 to 11,000 repeats) in intron 1 of the CNBP/ZNF9 gene. DM2 patients complain of skeletal muscle pain and weakness, myotonia (from 60% [166] to 85% [167]), hypogonadism (...
Living with other smokers has been associated with reduced smoking cessation, while having a ban on smoking in the home has been associated with increased cessation (75). In 1 study, a smoker’s chance of smoking was reduced by 67% if a spouse quit smoking and 36% if a friend quit ...