If this binding mode is utilized by LigIV, it is conceivable that the Glu331 and Glu427 could cooperatively coordinate the metal(s) through its hydration sphere, which could lessen the deleterious effect of mutating either residue individually. This hypothesis is consistent with the decrease, ...
4. The hydration energy and Bronsted acidity of the anion (solution behavior) These factors can be represented by the following chemical equilibria (Equation 1) LnMm++M′(O)xy−(aq)LxMn+(M′Ox)m-y (1) where, L—Ligand bound to silica polyamine composite, ...