MDS Is a Stem Cell Disorder After All. Cancer Cell 2014;25713-714.Jaiswal S, Ebert BL. MDS is a stem cell disorder after all. Cancer Cell 2014; 25: 713-4.Jaiswal S, Ebert BL. MDS is a stem cell disorder after all. Cancer Cell 2014; 25: 713-714....
Myelodysplastic syndromes (MDSs) represent clonal disorders mainly of the elderly that are characterized by ineffective hematopoiesis and an increased risk of transformation into acute myeloid leukemia. The pathogenesis of MDS is thought to evolve from a
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Unlike some pan-cancer oncogenes and tumour suppressor genes that drive transformation in virtually all cell types and cellular contexts, aneuploidy is not a universal promoter of tumorigenesis. Instead, recent studies suggest that aneuploidy is a context-dependent, cancer-type-specific oncogenic event ...
reported that only 4% of newly diagnosed MDS patients had been referred or were considered for transplantation referral; however, only 10% to 20% of surveyed hematologists had a practice based at a comprehensive cancer center or university hospital [21]. The percentage of patients referred for ...
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This paper presents the application of multidimensional scaling (MDS) analysis to data emerging from noninvasive lung function tests, namely the input respiratory impedance. The aim is to obtain a geometrical mapping of the diseases in a 3D space representation, allowing analysis of (dis)similarities...
Nonrandom variations in human cancer ESTs indicate that mRNA heterogeneity increases during carcinogenesis Marie Brulliard, Dalia Lorphelin, Olivier Collignon, Walter Lorphelin, Benoit Thouvenot, Emmanuel Gothié, Sandrine Jacquenet, Virginie Ogier, Olivier Roitel,Jean-Marie Monnez, Pierre Vallois, Fra...
cancer therapy, and b) the appearing frontier of LCM solitaryAquatic biologycell molecular evaluation incorporating proteomics with genomic, and transcriptomic analysis. The search method had been based on the combination of MeSH terms with expert refinement. LCM is complemented by a rich-set of ...
Significance of New Therapeutic Options in MDS and Other Blood Cancers Type of Breast Cancer in TROPION-PanTumor01 Affects Level of Benefit Insights From the AURIGA Trial in Multiple Myeloma Approved Therapies Considered for Patients With Graft-Vs-Host Disease Cilta-cel: Key Therapy for Unmet ...