The transcriptional network governing azole resistance is therefore highly complex and involves multiple regulators, some of which remain to be identified as our current models of this network are not able to explain all of the existing clinically significant mechanisms of azole resistance. We therefore...
DE pathway analysis (Supplementary Table 3) revealed the enrichment of KEGG pathways related to calcium and cAMP signaling, synaptic function and long-term potentiation in astrocyte subcluster 1 (Extended Data Fig. 7c), suggesting that this subcluster is associated with supporting synaptic function....
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Glembotski CC, Thuerauf DJ, Huang C, Vekich JA, Gottlieb RA, Doroudgar S (2012) Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion. J Biol Chem 287:25893–25904. https://doi...
At the center of Photosystem II is a cluster of ions, or electrically charged particles, specifically of manganese, calcium, and oxygen. This cluster is responsible for splitting the water molecules and is the focus of the new studies. “This step is insufficiently understood at the le...
The increase in the number of reactive cells for calbindin D28k from the premetamorphic period onward suggests that this protein may have a role in the differentiation of kidney function.Calcium-Binding Proteins in Health and Diseasedoi:10.1016/B978-0-12-521040-9.50104-2S. CHRISTAKOS...
use of a starch indicator to increase the sensitivity of iodometric titration to produce a more visible color change. Complexometric indicators include the chelating agent EDTA, which is used to titrate metal ions in solution, and Eriochrome Black T for the titration of calcium and magnesium ions....
Calcium-channel blockers do not alter the clinical efficacy of clopidogrel after myocardial infarction. J Am Coll Cardiol 2011;57:409–17. GoodCW, SteinhublSR, BrennanDM, LincoffAM, TopolEJ, BergerPB. Is there a clinically significant interaction between calcium channel antagonists and clopidogrel?
and find that its activation by reactive oxygen species (ROS) was acquired more than half-a-billion years ago along the vertebrate stem lineage. Functional experiments using genetically engineered mice and flies reveal ancestral vertebrates were poised to benefit from the union of ROS and CaMKII, ...
Hepatic ER stress occurs upon excessive accumulation of unfolded and misfolded proteins in the ER or when ER calcium is depleted. Three main sensors trigger ER signalling cascades aimed to restore ER homeostasis15(Fig.2). A large number of studies have established that exposure to saturated FFAs ...