doi:10.1158/1538-7445.AM2020-3177Background: Tumor mutational burden (TMB) has been emerging as a relatively new biomarker that is independent of PDL1 for the prediction of response to the immune checkpoint inhibitor (ICI) treatment. A recent study has shown that whole exome sequencing (WES)...
Volume 50, pages 1171–1188, (2020) Cite this article Download PDF You have full access to this open access article Foundations of Physics Aims and scope Submit manuscript Tomasz Bigaj & Antonio Vassallo 1884 Accesses 3 Citations 1 Altmetric Explore all metrics ...
Bioinformatics analysis of novel, potentially SMAD-dependent regulatory elements in the ID3 gene has allowed the identification of enhancers located between −3177 and −2660 bp upstream of the transcription start site (i.e., a so-called evolutionary conserved region [ECR] 1) and ECR2 located...
Consumer welfare refers to the individual benefits derived from the consumption of goods and services (https://stats.oecd.org/glossary/detail.asp?ID=3177). This is also known as ‘USMCA’ in the US and ‘T-MEC’ in Mexico. It supersedes the 1994 North American Trade Agreement (NAFTA). Th...
The primary antibodies BiP (9C50B12) (3177) and PERK (C33E10) (3192) were purchased from Cell Signaling Technologies. SPTLC1 antibodies were generated from our laboratory. SPTLC2 (CAT#: TA319780) antibodies were purchased from ORIGENE. The phospho-IRE1α (Ser724) from Novus biologicals (...
9, 3177 (2018). Article PubMed PubMed Central Google Scholar Classen, A. et al. Specialization of plant–pollinator interactions increases with temperature at Mt. Kilimanjaro. Ecol. Evol. 10, 2182–2195 (2020). Article PubMed PubMed Central Google Scholar Mayr, A. V. et al. Climate ...
3177 Accesses 4 Citations Metrics details Abstract Background The growing number of employed women has been associated with an increase in the prevalence of overweight and obesity in children. We sought to determine whether childhood overweight/obesity in Spain is associated with labour participation ...
Baud, V., Karin, M. Is NF-κB a good target for cancer therapy? Hopes and pitfalls.Nat Rev Drug Discov8, 33–40 (2009). https://doi.org/10.1038/nrd2781 Download citation Issue DateJanuary 2009 DOIhttps://doi.org/10.1038/nrd2781 ...
It is widely accepted that intellectual property legal requirements such as patents and data exclusivity can affect access to medicines, but to date there has not been a comprehensive review of the empirical evidence on this topic. The World Trade Organi
METHOD AND DEVICE FOR DETECTING A NON-CONDENSABLE PORTION OF A MEDIUM WHICH IS AT LEAST IN PART GASEOUSDisclosed is a method and a device for detecting a non-condensable portion of a medium, which has at least one condensable portion and is present at least partially in gaseous form, where...