Iron-dextran CAS:9004-66-4 MW:153.92348 MF:FeH2O4S Iron-dextran, with the chemical formula (C6H10O5)nFe, is a complex compound consisting of iron and dextran. It is commonly used as an iron supplement in the treatment of iron deficiency anemia. Iron-dextran is administered intravenously and...
Iron-dextran $25.00/ 1kg 2024-10-25 CAS:9004-66-4 Min. Order: 1kg Purity: 0.99 Supply Ability: 20 tons Related articles Iron-Dextran: Mechanism of Action, Pharmacokinetics and Adverse Effects Iron-dextran treats iron deficiency anemia by delivering iron for transport via transferrin, but may ...
et al. The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action. Mol. Pharmacol. 83, 179–190 (2013). Article CAS PubMed Google Scholar Liu, Y. T. et al. Chronic oxidative stress causes ...
Thomas Sydenham recommended iron salts as treatment for chlorosis, but treatment with iron was controversial until the 20th century, when its mechanism of action was more fully elucidated. SymptomsIron deficiency anemia is characterized by pallor, fatigue and weakness. Because it tends to develop ...
12.1 Mechanism of ActionIron is an aqueous complex of poly-nuclear Iron (Polysaccharide-Iron Complex) (III)-hydroxide in sucrose. Following intravenous administration, Iron (Polysaccharide-Iron Complex) is dissociated into Iron (Polysaccharide-Iron Complex) and sucrose and the Iron (Polysaccharide-Iron...
Mechanism of exacerbation of rheumatoid synovitis by total-dose iron-dextran infusion: in-vivo demonstration of iron-promoted oxidant stress. Lancet 1987;1:69-72.Winyard PG,Chrico S, Blake DR, Gutteridge JMC, Lunec J. Mechanism of exacerbation of rheumatoid synovitis by total-dose iron-dextran...
Mechanism of Action Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin Pharmacokinetics Half-Life: 6 hr Onset: 7-9 days (serum ferritin peak) Peak Plasma Time: 10 days Absorption: Within 72 hr (IM) Excretion: Minimal through urine ...
Iron-overload cardiomyopathy is a prevalent cause of heart failure on a world-wide basis and is a major cause of mortality and morbidity in patients with secondary iron-overload and genetic hemochromatosis. We investigated the therapeutic effects of resv
dextran-coated iron oxide NPs better the therapeutic effects on human mesenchymal stem cells (hMSCs) in an animal mouse model of PD. The dextran-coated iron oxide NPs stimulate the movement capability hMSCs to lesioned dopaminergic neurons and prevented the effect of hMSCs on the loss of DANs....
rheumatoid arthritis, pneumonia, cardiovascular disease, and sepsis [214,215]. Yang et al. found that Schizandrin B can inhibit ferroptosis and alleviate myocardial injury in diabetic mice, and its mechanism of action may be related to the activation of the Nrf2/HO-1/GPX4 signaling pathway [...