The effect of intravenously infused iron-dextran (Imferon) on the progression of antigen induced monarticular arthritis in rabbits was studied. A rapid deposition of iron and apoferritin in the synovia of arthritis joints occurred after infusion of iron-dextran during either the acute or chronic ...
One had an immediate anaphylactoid reaction; th... KN Lloyd,P Williams - 《British Medical Journal》 被引量: 45发表: 1970年 TOTAL DOSE INFUSION IRON DEXTRAN THERAPY IN PREDIALYSIS CHRONIC RENAL FAILURE PATIENTS. BACKGROUND: Intravenous iron therapy is now the standard modality of iron ...
Iron-dextran CAS:9004-66-4 MW:153.92348 MF:FeH2O4S Iron-dextran, with the chemical formula (C6H10O5)nFe, is a complex compound consisting of iron and dextran. It is commonly used as an iron supplement in the treatment of iron deficiency anemia. Iron-dextran is administered intravenously and...
Randomized cross-over study of adverse reactions and cost implications of intravenous push compared with infusion of iron dextran in hemodialysis patients In many dialysis centers, iron dextran is administered by intravenous infusion rather than intravenous push (the method of administration recommended ...
ID, Iron dextran;LMW, low molecular weight;N, no;TDI, total dose infusion;Y, yes. ∗ Allowing single dose administration of a patient’s entire iron requirement, rather than needing multiple smaller doses. Hypersensitivity reactions
The extent of risk for anaphylactic-type reactions following exposure to any specific iron dextran product is unknown and may vary among products; if hypersensitivity reactions occur during administration, stop infusion immediately and manage reaction medically If hypersensitivity reactions occur during admin...
In a randomized, open-label, dose-ranging trial for Iron (Polysaccharide-Iron Complex) maintenance treatment with Iron (Polysaccharide-Iron Complex) in pediatric patients with CKD on stable erythropoietin therapy , at least one treatment-emergent adverse reaction was experienced by 57% (27/47) of ...
Life-threatening Reaction to Iron Dextran: Protocol for Induction of Tolerance. J Investig Allergol Clin Immunol [Internet]. 2016 [cited 2017 Jul 27];26(1):48–49. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27012016. Google Scholar 11. Rodríguez-Jiménez B, Domínguez-Ortega J,...
Overall, there was no difference between the dose groups in the time from the last IV iron infusion to death (≤1000 mg: 19 weeks; >1000 mg: 21 weeks). Discussion The real-world, observational NIMO-CKD-UK study showed that a higher dose IV iron regimen (>1000 mg) ...
The previous generation of IV iron preparations, specifically high-molecular-weight iron dextran, were associated with a high risk of severe hypersensitivity reactions, which restricted their use. These formulations have been discontinued due to their unfavorable safety profile and high risk of a serious...