Teng TS, Lin B, Manser E, Ng DC, Cao X. Stat3 promotes directional cell migration by regulating Rac1 activity via its activator betaPIX. J Cell Sci. 2009;122:4150–9.
Kuo L, Davies MJ, Cannon S, Chilian WM (1992) Pathophysiological consequences of atherosclerosis extent into the coronary microcirculation; restauration of endothelium-dependent responses by L-arginine. Circ Res 70:465–476 PubMedCASGoogle Scholar Lautamäki R, Brown T, Merrill J, Bengel F (200...
Recent developments in high-throughput sequencing technologies and microarray techniques enable scientists to conduct comprehensive analyses on the abundance, composition, expression profile and molecular function of circRNAs [16]. So far, large amounts of circRNAs have been successfully identified in a ...
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Single-cell RNA sequencing (scRNA-seq), a technology that analyzes transcriptomes of complex tissues at single-cell levels, can identify differential gene expression and epigenetic factors caused by mutations in unicellular genomes, as well as new cell-s
Stroke is a major global disability cause, and genetic variables for multifactorial illnesses like stroke are crucial for precision medicine. The purpose of this study is to see if genetic variants in the MTHFR gene are associated with a higher risk of i
The epicardium, the mesothelial envelope of the vertebrate heart, is the source of multiple cardiac cell lineages during embryonic development and provides signals that are essential to myocardial growth and repair. Here we generate self-organizing human
Diabetic cardiomyopathy (DCM) is a critical complication that poses a significant threat to the health of patients with diabetes. The intricate pathological mechanisms of DCM cause diastolic dysfunction, followed by impaired systolic function in the late
Using rat model allowed us to investigate the MANF temporal expression profile in more detail as well as to use double immunofluorescence technique and identify MANF-positive cell phenotypes. In the non-stroke control brain MANF immunoreactivity was neuronal (Fig. 2a), as we have seen and ...
The relative balance of suppressive mechanisms used by individual tTreg may depend on target cells and tissue milieu. Mature tTreg can undergo further differentiation in the periphery or may modulate their gene expression profile in response to activation state, distinctive milieus, or interactions with...