Parkinson’s disease PFC: Prefrontal cortex PSP: Postsynaptic potentials QSU: Questionnaire on Smoking Urges SCC: Subcallosal cingulate STN: Subthalamic nucleus SUD: Substance use disorders tDCS: Transcranial Direct Current Stimulation vmPFC: Ventromedial prefrontal cortex VS: Ventral striatum...
It has also been revealed that AD is a disorder of protein aggregation in which two main proteins are involved (Duyckaerts et al., 2009). Amyloid-β (Aβ) accumulates in extracellular parenchymal amyloid plaques as well as in the walls of the cerebrovasculature to form cerebral amyloid ...
In disease paradigms, e.g. the neurotoxin 6-hydroxydopamine (6-OHDA) rat Parkinson’s disease model, VIP increased ADNP expression in glutamic acid decarboxylase (GAD) expressing in striatal neurons (Yelkenli et al., 2016). In a rotenone mouse model of Parkinson’s disease, a complex dysregula...
the prevalence of lower urinary tract dysfunction (LUTD) and related symptoms in neurological conditions such as spinal cord injury (SCI), multiple sclerosis (MS), Parkinson’s disease (PD), and stroke,
A physiological role in promoting angiogenesis and neuronal survival has also emerged for angiogenin following the discovery of genetic mutations of the gene encoding for this protein in familial forms of ALS and Parkinson’s disease32. Emphasis on the potential role of integrins in disease ...
As with other neurodegenerative diseases, the greatest unmet D-AP5 need is the development of biomarkers and disease-modifying therapies. The risk for developing Parkinson’s is multifactorial and results from an interplay between advancing age, environmental and genetic factors. The attributable risk ...
1. Introduction Parkinson's disease (PD) is a disorder characterized by the selective death of dopamin- ergic (DA) neurons in the substantia nigra pars compacta (SN) of the midbrain, commonly seen in older adults. It is closely related to the abnormal increase in reactive oxygen species (...
Neurotensin NTS1-dopamine D2 receptor-receptor interactions in putative receptor heteromers: relevance for Parkinson's disease and schizophrenia. Ferraro L, Beggiato S, Borroto-Escuela DO, Ravani L, O'Connor WT, Tomasini MC, Borelli AC, Agnati LF, Antonelli T, Tanganelli S, Fuxe K. Curr ...
Hague Aide in Power Battle with Parkinson
The ventral pallidum (VP) is an important structure in processing reward. The VP may be the only brain structure where localized lesions in rats replace no