Background Journal impact factor (IF) is the leading method of scholarly assessment in today's research world, influencing where scholars submit their research and where funders distribute their resources. COVID-19, one of the most serious health crises, resulted in an unprecedented surge of public...
Lung cancer is the leading cause of cancer-associated mortality worldwide1. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACERx study. This project aims to decipher lung ...
Debridement and wound closure of open fractures: The impact of the time factor on infection rates Author links open overlay panelD.J. Crowley a, N.K. Kanakaris a, P.V. Giannoudis bShow more Add to Mendeley Share Cite https://doi.org/10.1016/j.injury.2007.01.012Get rights and content...
Historically, sunitinib (Sutent; Pfizer Inc) was among the first VEGF-targeted TKIs approved for first-line treatment of advanced ccRCC.6In clinical trials examining other first-line treatment options for metastatic ccRCC, sunitinib is typica...
and elevated blood pressure levels [53,54,55]. For instance, it has been shown that butyrate can stabilize the hypoxia-inducible factor-1, promoting vascularization and reducing blood pressure [56]. Therefore, the abundance of butyrate-producing bacteria in the human gut is associated with lower...
TGF-β transforming growth factor-β Tregs regulatory T cells 1. Introduction Food allergy has been increasing in prevalence over the last several decades. Food allergies in children may ultimately resolve and disappear. However, there are cases in which food allergies do not resolve with age and...
which typically overlook PD-L1 expression as an influencing factor on treatment efficacy, this trial recognizes the significance of analyzing such end points. However, it is worth noting that most trials lack comprehensive analyses, including post hoc assessments, to evaluate the...
Med. https://doi.org/10.1056/NEJMc2211055 (2022). Article PubMed PubMed Central Google Scholar Hansen, C. H. et al. Risk of reinfection, vaccine protection, and severity of infection with the BA.5 omicron subvariant: a Danish nation-wide population-based study. SSRN Electron. J. ...
The presence of PH is an independent risk factor of death in patients with COPD [2, 5, 11]. Some studies report that ET is associated with elevated pulmonary arterial pressure (PAP) in COPD [12,13,14]. There is also a study indicating that 22% of 171 idiopathic pulmonary arterial hyper...
Respiratory infections can cause wheezing illnesses in children of all ages and also influence the development and severity of asthma in several ways. First, viral wheezing episodes during infancy are a critical risk factor for asthma inception. Once asthma is established, viral upper respiratory tract...