对于现在科学界一切跟着影响因子（Impact Factor）转的潮流，算是浇上了一点冷水，也表达了JBC这个百年老...
The aim of the present study was to investigate the impact of PKCdelta on the regulation of the transcriptional activity of the human ERalpha. By using 12-O-tetradecanoylphorbol-13-acetate (TPA), Bryostatin1 and Rottlerin, we show that active PKCdelta is a proproliferative factor in estrogen-...
Analysis of biomolecular interactions has demonstrated that pEVs contain numerous cytoplasmic proteins that bind to porcine gastric mucins, such as elongation factor Tu, phosphoglycerate kinase, and heat shock proteins. Consequently, pEVs enhance the colonization of probiotics by transporting bacterial ...
Receptor status is an important prognostic factor among women with breast cancer. The aim of this study was to evaluate the effect of r... CE Fasola,IC Gibbs,SG Soltys,... - 《Cancer Research》 被引量: 0发表: 2012年 P53 gene mutations and steroid receptor status in breast cancer. ...
13,14 The tissue abnormalities of these autophagy-defective mice are often accompanied by the accumulation of p62 and ubiquitinated proteins. In the liver, p62 sequesters the E3 ligase KEAP1 and stabilizes the antioxidant transcription factor NRF2/NFE2L2.15 The deletion of p62 or NRF2 abolishes ...
Shaikhali J, Heiber I, Seidel T, Ströher E, Hiltscher H, Birkmann S, Dietz KJ, Baier M (2008) The redox-sensitive transcription factor Rap2.4a controls nuclear expression of 2-Cys peroxiredoxin A and other chloroplast antioxidant enzymes. BMC Plant Biol 8:48. https://doi.org/10.1186...
factor shaped research into prenatal influences on kidney development, reinforcing the developmental origins of kidney disease. Together, the work of Barker and Brenner led to a broader understanding that kidney disease could originatein utero, influenced by maternal diet, stress, and other factors ...
The present study reports on the ability of four MSH peptides to control intracellular peroxide levels and glutathione peroxidase (GPx) activity in pigmentary and nonpigmentary cells. In human HBL melanoma and HaCaT keratinocytes tumor necrosis factor α and H2O2 both activated GPx in a time- ...
Furthermore, the TH1/TH2 balance is affected by zinc. During zinc deficiency, the production of TH1 cytokines, in particular IFN-γ, IL-2, and tumor necrosis factor (TNF)-α is reduced, whereas the levels of the TH2 cytokines IL-4, IL-6, and IL-10 were not affected in cell culture...
While the calcium phosphate granules may induce changes in morphology by mechanically disrupting membranes, it is plausible that free calcium interacts with proteins regulating inner membrane and cristae maintenance (namely the optic atrophic factor 1 and the mitochondrial contact site and cristae ...