[45,46]. Disc-derived DILP8 induces a developmental delay through a neuronal relay that involves neurons expressing the DILP8 receptor Lgr3 (a G-protei key role in a checkpoint mechanism that enables the organis
At adult ecdysis time, the wing disc-derived structures phenotypically differ between workers and queens (Add- itional file 14: Supplementary Figure 7) [35, 43]. There- fore, execution of the wing discs metamorphic program embodies differential gene expression between castes, which is more ...
Much of the complex anatomy of a holometabolous insect is built from disc-shaped epithelial structures found inside the larva, i.e., the imaginal discs, which undergo a rapid differentiation during metamorphosis. Imaginal discs-derived structures, like wings, are built through the action of genes...