mitogen-activated protein kinase (MAPK)Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway. Some studies have shown that statins may have the potential to inhibit intervertebral disk (IVD) degeneration (IDD). Interleukin (IL)-1 beta, a catabolic cytokine, is a key...
机译:人β-防御素(-1,-2,-3,-4)和Cathelicidin LL-37通过p38和ERK MAPK激活原代人角质形成细胞诱导IL-18分泌。 2. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. [J] . Niyonsaba F, Ushio H, Hara...
IL-1[beta] induces murine airway 5-HT.sub.2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism.(Research)(5-hydroxytryptamine, interleukin)Zhang, YapingCardell, LarsOlafAdner, Mikael
Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells. J Cell Physiol. 2004; 5 :5.Lin F-S, Lin C-C, Chien C-C, Luo S-F, Yang C-M: Involvement of p42/p44 MAPK, JNK, and NF-κB in IL-1β-induced ICAM-...
IL1beta down- regulation of sex hormone-binding globulin production by decreasing HNF- 4alpha via MEK-1/2 and JNK MAPK pathways. Mol Endocrinol. 2012;26:1917-27.Simo R, Barbosa-Desongles A, Hernandez C, Selva DM. IL1beta down-regulation of sex hormone-binding globulin...
Here, we assess the ability of Nepetin to alleviate the inflammatory responses of ARPE-19 cells induced by interleukin (IL)-1 beta.Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapieChen, XiHan, RuifangHao, PengWang, LimingLiu, MeixinJin, MeihuaKong, DexinLi, Xuan...
Aqueous extract of Codium fragile alleviates osteoarthritis through the MAPK/NF-kappa B pathways in IL-1 beta-induced rat primary chondrocytes and a rat osteoarthritis modelOsteoarthritisCodium fragile (Suringar) HariotNitric oxideMMP-13ADAMTS-4
Publication » O11 CURCUMIN SUPPRESSES P38 MAPK ACTIVATION, REDUCES IL-1BETA AND MMP-3, AND ENHANCES IL-10 EXPRESSION IN THE MUCOSA OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE.doi:10.1016/S1873-9954(09)70012-6Epstein J.MacDonald T.T....
WANG M,CRISOSTOMO P,LILLEMOE K,et al.Deficiency of TNFR1 protects myocardium through STAT3,SOCS3,and IL-6, but not p38 MAPK or IL-1 beta.Am Colle Surg. 2006WANG M,CRISOSTOMO P,LILLEMOE K,et al.Deficiency of TNFR1 protects myocardium through STAT3,SOCS3,and IL-6, but not p38 ...