IL-18IL-1 betainflammasomechronic hepatitis Bhepatocellular carcinomacirrhosisChronic inflammation is the main risk factor for induction of liver cirrhosis and also hepatocellular carcinoma in chronic hepatitis B (CHB) patients. Although our knowledge is growing regarding molecular mechanisms of immune ...
There was a significant correlation between psychiatric morbidity, serum levels of IL-1beta, IL-12, IL-18, TNF-alpha and disease activity measurements. We have to view rheumatoid arthritis as a psycho-immumological disorder rather than an autoimmune disease. Furthermore, the studied cytokines may...
Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections The inflammasome is an important innate immune pathway that regulates at least two host responses protective against infections: (1) secretion of the proin... M Sahoo,Ivonne Ceballos-Olvera,LD Barrio,... - 《Scientific World...
The disks were inserted subcutaneously in rats for 1, 3, 12, 18, 24 and 48 h. Interleukin-1alpha (IL-1alpha), IL-1beta and tumor necrosis factor-alpha (TNF-alpha) concentrations were measured in vivo around the materials, in sham operated sites, and after ex vivo incubation of surface...
IL-1β and IL-18 are proinflammatory cytokines that contribute to renal immune complex disease, but whether IL-1β and IL-18 are mediators of intrinsic glo... Julia,Lichtnekert,Onkar,... - 《Plos One》 被引量: 100发表: 2011年 Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and...
Objective To observe the inhibitory effect of Tongxinluo(TXL) on coronary vaso spasm in small swine in vivo,and to investigate its possible acting mechanism.Methods The model of coronary atherosclerosis in 16 male small swines was established by left thoracotomy after anesthesia,isolated the sections...
Populational aging is marked by chronic noncommunicable diseases, such as metabolic syndrome (MetS). IL-10 and IL-1β are pleiotropic cytokines with multiple biological effects linked to metabolic disorders. This cross-sectional study assessed 193 partic
Functional IL-18 Is Produced by Primary Pancreatic Mouse Islets and NIT-1 Beta Cells and Participates in the Progression towards Destructive Insulitis. Functional IL-18 is produced by primary pancreatic mouse islets and NIT-1 beta cells and participates in the progression towards destructive insulitis...
Stem Cell Research & Therapy (2015) 6:135 DOI 10.1186/s13287-015-0123-0 RESEARCH Open Access CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells Mashael Al-toub1, Radhakrishnan Vishnubalaji1, R...
To clarify the involvement of TNF alpha and IL-1 beta in the initiation of fibrotic lung diseases, their localization was examined by immunohistochemistry. Fibrotic lung diseases observed were classified into acute and old pulmonary fibrotic changes. The