目的检测未抗病毒治疗的HBV相关肝硬化患者外周血调节性T细胞(treg细胞)及其亚群频率和IL-1beta,IL-6,IL-10水平,以及它们与临床生化指标,HBV DNA水平,E抗原的关系,探讨treg细胞及其亚群频率和IL-1beta,IL-6,IL-10水平在HBV相关肝硬化患者发病过程中的变化及临床意义.方法对20例健康对照组,17例慢性乙型肝炎组,38...
ROSSER E. Gut-microbiota induced IL-1b and IL-6 control the differentiation of regulatory B cells[J]. Rheumatology, 2013, 15(3): 184-192. DOI:... E Rosser - 《Journal of Computing Sciences in Colleges》 被引量: 6发表: 2013年 Regulatory B cells as inhibitors of immune responses and ...
IL-1 beta and IL-6 enzyme-linked immunosorbent assays (ELISAs) were done on supernatants prepared from mouse parotid acinar cell (MPAC) preparations unstimulated or stimulated between 0 and 10 min with 10(-5) M norepinephrine at 37 degrees C. MPACs were fixed in paraformaldehyde, frozen ...
IL-1β(白细胞介素1 β)是在多种细胞中产生的促炎细胞因子,包括单核细胞、组织巨噬细胞、角质形成细胞和其他上皮细胞。[1][2]它被合成为pro-IL-1β ,其在促炎蛋白酶caspase-1的帮助下变为活性形式的IL-1β。[3]IL-1β 属于IL-1 基因家族。[4]该基因定位于人类染色体 2q14。[5]重组人IL-1β是...
背景说明:Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates...
IL-1β is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses including the activation of B and T cells. Recombinant human IL-1β is a 17.0 kDa protein containing 153 amino acid residues. 序列 重组人白介素-1β蛋白产品,又称Catabolin, Lymphocyte-activating...
IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both protei...
The epithelial to mesenchymal transition (EMT) is a multi-factorial biological mechanism involved in renal and hepatic fibrosis and the IL-1 beta has been assumed as a mediator of this process although data are not exhaustive. Therefore, the aim of our s
Recombinant human IL-1 beta 偶联物 Unconjugated 形式 Liquid 浓度 1.0 mg/mL 纯化类型 Protein G 保存液 PBS 内含物 no preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_223567 产品详细信息 M421B targets IL-1 beta in ELISA, and WB applications and shows...
Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions.IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha. These cytokines play i...