Cells were exposed to human recombinant interleukin-1 beta (IL-1 beta; 20-100 pg/ml) or interleukin-6 (IL-6; 1-4 ng/ml) in the presence of indomethacin (1 microgram/ml) for up to 5 days. Proliferation of ASM cells was assessed with two techniques, direct counting of cells with a...
IL-1B主要由单核细胞,巨噬细胞和树突细胞在微生物诱导后产生。白细胞介素6(IL-6)是一种多效细胞因子,由许多不同的细胞类型产生,在多种功能中发挥作用,如免疫反应,急性期反应和造血功能。 除此之外,它还增加了体外活化B细胞的抗体产生。 产品描述 FluoroSpot测定是ELISpot测定的创造性发展并且使用荧光检测而不是...
IL-1, secreted by human embryos and trophoblast cells, is important for successful implantation and pregnancy. We previously reported that IL-1beta induced... Y Hirota,Y Osuga,A Hasegawa,... - 《Endocrinology》 被引量: 0发表: 2009年 Effects of interleukin-6 (IL-6) on cytotrophoblastic cel...
enhanced production of il-1β βββ and il-6 following endotoxin challenge in rats with dietary magnesium deficiency We have previously shown that interleukin (IL)-1beta and tumour necrosis factor (TNF)-alpha mRNA levels in rat alveolar macrophages are increased in by end... M Nakagawa,H Oo...
目的检测未抗病毒治疗的HBV相关肝硬化患者外周血调节性T细胞(treg细胞)及其亚群频率和IL-1beta,IL-6,IL-10水平,以及它们与临床生化指标,HBV DNA水平,E抗原的关系,探讨treg细胞及其亚群频率和IL-1beta,IL-6,IL-10水平在HBV相关肝硬化患者发病过程中的变化及临床意义.方法对20例健康对照组,17例慢性乙型肝炎组,38...
Serum levels of IL-1 beta, sIL-2R, IL-6, IL-8, and TNF-alpha in febrile children with cancer and neutropenia 1385/MO:18:1:51Soker M, Colpan L, Ece A, Devecioglu C, Haspolat K. Serum levels of IL-1 beta, sIL-2R, IL-6, IL-8, and TNF-alpha in ... M Soker,Leyla olpa...
Finally, we conclude that Type 1 diabetic patients with or without AP did not express higher LPS-induced TNF-a, IL-1b and IL-6 levels than controls. However, the PGE2 levels released were significantly higher than those detected in controls. 展开 关键词: TNF-alpha IL-1 beta IL-6 PGE(...
IL-1是急性期免疫反应的主要调节因子, 它在T 细胞激活, 诱导IL-2产生起着基本的作用. 这些调节作用的产生主要通过作用在神经系统,骨髓干细胞而发生作用. 这些调节作用大多数是IL-1β直接产生的, 但有些是与其它细胞因子如IL-6, IFN, TNF 协同作用下发挥效应的.正常人血液中不含IL-1β或者含量很底, IL-1...
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1尾 and IL-6 production through a caspase 1-dependent mechanism Kim, IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase ...
Cardiovascular diseases (CVDs) are a leading cause of global morbidity and mortality, significantly driven by chronic inflammation. Interleukin-6 (IL-6) and interleukin-1β (IL-1β) are critical inflammatory cytokines implicated in CVD progression. This