Modulation of IL-2,IFN-gamma,TNF-alpha and IL-4 production in mice of different ages by thymopentin[J].Int J lmmunopharmacol,1992.1029-1035.Cillari E, Milano S, Perego R, et al. Modulation of IL-2, IFN-gamma, TNF-alpha and IL-4 production in mice of different ages by thymopentin....
Analysis of IL-2, IFN-gamma and TNF-alpha production, alpha5 beta1 integrins and actin filaments distribution in peritoneal mouse macrophages treated with ... Analysis of IL-2, IFN-γ and TNF-α production, α5β1 integrins and actin filaments distribution in peritoneal mouse macrophages ...
摘要: 目的 观察特发性血小板减少性紫癜(ITP)患者治疗前、后血清白细胞介素(IL)、肿瘤坏死因子-α(TNF-α)与γ-干扰素(IFN-γ)水平的变化。方法采用酶联免疫吸附试验(ELISA)测定53例ITP患者治疗前、后及50名正常对照者血清IL-2、 IL-4、 IL-6、 IL-10、TNF-α、IFN-γ水平,并对检测结果进行分析。结果...
辅助性T细胞以及细胞毒性T细胞产生IFN-Y是TH1型表型的标志,因此,IFN-Y的高水平产生通常与针对细胞内病原体的有效宿主防御相关。白细胞介素-2(IL-2)仅由活化的T细胞产生。IL-2促进抗原活化T细胞和NK细胞的增殖,分化和存活。肿瘤坏死因子-a(TNF-a)由许多不同的细胞类型产生,例如单核细胞,巨噬细胞,T细胞和B细胞...
(IL),tumornecrosisfactor—alpha(TNF—d) andgamma—interferon (IFN一)inidiopathicthrombocytopenicpurpura(ITP)patientsbeforeandaftertreatment. Methods TheconcentrationsofselMm IL-2,4,6,10,TNF一 andIFN一 wererespectivelymeasuredbyenzyme·linked immunosorbentassay(ELISA)in53ITPpatientsbeforeandaftertreatmentand50...
Objective To evaluate the changes of serum interleukin (IL) , tumor necrosis factor-alpha ( TNF-α) and gamma-interferon (IFN-γ) in idiopathic thrombocytopenic purpura (ITP) patients before and after treatment. Methods The concentrations of serum IL-2,4,6,10, TNF-α and IFN-7 were respect...
测定在第1组和第2组中,测定血清细胞因子(IFN-γ、IL-6、TNF-α、IL-17A、IL-21、IL-22和IL-23)浓度。同样,在年龄和性别匹配的健康对照组(HC)中也测量了这些浓度。在第1组和第2组的所有患者中,在完成1年治疗后,测量生物疗法开始时的血清细胞因子浓度。使用MSD S-PLEX人类IL-17A试剂盒(#K151C3S-1,Me...
The latter was significantly correlated to up-regulation of IL-2, TNF-alpha, IFN-gamma and iNOS mRNA expression. Expression of remaining cytokines and percentage of apoptotic cells showed no group-specific changes. The results indicate an initial infiltration of CD4+ T cells followed by increased ...
Generation of TNF alpha , IFN gamma , IL - 6 ,IL - 4 and IL - 10 in mouse serum from trichimellosis : effect of the anti - inplammatory compound 4 - DPD. Immunol Lett , 1996 , 49 (3) : 179Frydas S, Karagouni E, Dotsika E, Reale M, Barbacane RC, Vlemmas I, Anogia...
Basal levels of cytokines including IL-2, IL-4, IL-6, IL-8, IL-10, TNF-alpha, and IFN-gamma showed a transit elevation followed by stable status in peripheral blood, especially the level of IL-6, which is the central mediator of toxicity associated with cytokine release syndrome (CRS)...