Gene SummaryProbable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2. IGFR1_HUMAN,Q9H665 包装清单: 产品编号产品名称包装 L13035pLenti-IGFLR1-sgRNA5µg —说明书1份 ...
Insulin Growth Factor-like Family Receptor 1 (IGFLR1) is a 355 amino acid (aa) type 1a transmembrane protein that was identified in a screen for binding partners of human IGFL-1. Mature human IGFLR1 consists of an extracellular domain (ECD) with two putative cysteine-rich domains (CRDs),...
The INSR/IGF1R Receptor FamilyInsulinInsulin-like growth factor-1 (IGF1IGF2Insulin receptorIGF1 receptorThe insulin/insulin-like growth factors (IGFs) constitute a network of ligands, cell-surface receptors, and binding proteins involved in the regulation of multiple physiological and pathological ...
Insulin Growth Factor-like Family Receptor 1 (IGFLR1) is a 355 amino acid (aa) type 1a transmembrane protein that was identified in a screen for binding partners of human IGFL1 (1). Mature human IGFLR1 consists of an extracellular domain (ECD) with two putative cysteine-rich domains (CRDs...
Receptor, IGF Type 1Signal TransductionMutationChildNeoplasmsThe insulin-like growth factor (IGF) family consists of ligands (IGF-I, IGF-II, insulin), several receptors (including IGF-1R), and six binding proteins (IGFBP-1 through IGFBP-6). Members of this family regulate key cellular ...
Annenkov, A. (2012). Insulin-like Growth Factor Receptor Type I (IGF1R) Signaling and Inflammation. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0461-4_326
Crosstalk Between Epidermal Growth Factor Receptor- and Insulin-Like Growth Factor-1 Receptor Signaling: Implications for Cancer Therapy Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor-1 receptor (IGF-1R) can contribute to tumor development and -progressio... J....
Abbreviations – ALL: acute lymphoblastic leukemia; AML: acute myeloid leukemia; ER+: estrogen receptor positive; HNSCC: Head and neck squamous cell cancer; IGF2BP1: insulin-like growth factor 2 mRNA binding protein 1; IGFBP-rP1: insulin-like growth factor binding protein related peptide 1; NSCL...
Growth hormone releasing hormone (GHRH) and the GHRH receptor. Rev Endocr Metab Disord. 2002;3:313–23. Article CAS PubMed Google Scholar Martin-Estal I, De La Garza R, Castilla-Cortazar I. Intrauterine growth retardation (IUGR) as a novel condition of insulin-like growth factor-I (IGF...
Valentinis, B., Romano, G., Peruzzi, F., Morrione, A., Prisco, M., Soddu, S., Cristofanelli, B., Sacchi, A., & Baserga, R. (1999). Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways.The Jour...