We demonstrated similarities and differences in the effects of IFN-alpha and IFN-beta compared to IFN-gamma on the production of factors deposited in the Weibel-Palade bodies in cultures of endothelial cells (intact and infected with herpes simplex virus 1). IFN-alpha and IFN-beta reduced the ...
() alpha/beta production was detected as early as 4 hours PI in female spleen cultures infected with -D at an MOI of 0.1 while no /beta activity was found in comparably infected male spleen cultures. Inhibiting /beta activity in the virus-infected spleen cultures during the first 20 hours ...
and rat cultured mast cells, RCMC) and mast cells from the rat body cavity were used to test the hypothesis that IFN-α/β and IFN-γ inhibit tumor necrosis factor α (TNF-α)-mediated cytotoxicity by depressing the steady-state levels of mRNA for TNF-α....
The macrophage cytokine IL-1beta in combination with IFN-gamma and TNF-alpha, plays an important role for beta-cell dysfunction and death. Signal ... D. L. and Eizirik,T Mandrup-Poulsen - 《Diabetologia》 被引量: 1514发表: 2002年 Cloning of the human gene for intercellular adhesion molec...
Natural killer T (NKT) cells are CD1d-restricted lymphoid cells and are characterized by an invariant T-cell receptor, which in humans consists of a Valpha24 chain paired with a Vbeta11 chain. These cells are known for their rapid production of large amounts of cytokines (e.g., IFN-gam...
Polymorphism in the genes of alpha and beta tumor necrosis factors (TNF α and TNF-β) and gamma interferon (IFN-γ) among Iranian women with breast cancer. Cancer Lett 2005;223:113-9.Kamali-Sarvestani E,Merat A,Talei AR.Polymorphism in the genes of alpha and beta tumor necrosis ...
IL-1beta, IL-6, IL-8, IL-10, IFN-gamma, TNF-alpha and its relationship with lipid parameters in patients with major depression. Metabolic brain disease 27, 425-430.Hocaoğlu C, Kural B, Aliyazicioglu R, Deger O, Cengiz S. IL-1 β , IL-6, IL-8...
干扰素-γ蛋白,重组小鼠 The Interferon-gamma protein (or IFN-gamma protein) is a regulatory protein produced by activated NK cells & CD4+TCRalpha/beta+, CD8+TCRalpha/beta+ & TCRgamma/delta+ T cells.; Synonyms: IFN γ,IFN g,IFN gamma,INF γ,INF g,INF gamm
Critical role of IFN-alpha/beta and IFN-gamma in the regulation of airway inflammation. Nippon Rinsho. 2006 Jul;64(7):1260-8.Ashino S,Nishimura T.The critical role of IFN-alpha/beta and IFN-gamma in the regulation of airway inflammation. Japanese Journal of Clinical Medicine . 2006...
Interferon (IFN)-alpha and -beta are produced by virus-infected cells; IFN-gamma is produced as a primary response of T lymphocytes to mitogenic stimulation, IFN-gamma gene activation being brought about by changes in Ca2+ and phosphatidyl inositol metabolism. IFNs act by binding to cell ...