Nima Motamed 4, Mansooreh Maadi 1, Hossein Ajdarkosh 1, Esmaeel Gholizadeh 1, Samira Chaibakhsh 5 & Farhad Zamani 1* Nonalcoholic fatty liver disease (NAFLD) is expanding as a global health problem with approximately 25% of the world's population affected by ...
Reporting of statistics using ICD coding has been found to underestimate disease and injury causes, largely due to missing/incomplete codes or a lack of specificity in the codes used [3–10]. Given the lack of © The Author(s) 2024. Open Access This article is licensed under a Creative ...
However, a large number of E3 substrate interactions (ESIs) and DUB substrate interactions (DSIs) remain elusive. Here, we present DeepUSI, a deep learning-based framework to identify ESIs and DSIs using the rich information present in protein sequences. Utilizing the collected golden standard ...
The Revolution in Large-Scale and High-Throughput Proteomics An Introduction to Proteome-wide Systems Genetics to Identify Regulatory Networks of Complex Phenotypes Applications of Proteome-wide Systems Genetics in Eukaryotes Assigning Causality to Assess Functional Variants Regulating Proteins and Phenotypes Co...
We observed fixing the lead SNP as a covariate can help to distinguish additional close association signal(s). Thereafter, using the mammalian phenotype database, we successfully found candidate genes, in concordance with previous studies, demonstrating the power of this strategy. Secondly, we used ...
Development of a core set of ARG PowerCore is a program that applies the advanced M-strategy using a heuristic search (Kim et al. 2007). It was used to constitute a core set from the entire collection of ARG investigated (https://genebank.rda.go.kr/powercore/). Using PowerCore, four...
Internal and Emergency Medicine (2024) 19:745–756 https://doi.org/10.1007/s11739-023-03441-2 IM - ORIGINAL Accuracy of a sequential algorithm based on FIB‑4 and ELF to identify high‑risk advanced liver fibrosis at the primary care level Pablo Gabriel‑Medina1,2,3...
Adoptive immunotherapy with tumour-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as PD-1, for tumour-specific T-cell enrichment, and the identification of predictive factors that help identify those patients capable o
We refined existing ICD-9-CM definitions for diagnostic clusters of common pain conditions consistent with the US National Pain Strategy and developed corresponding ICD-10-CM definitions. We then assessed the stability of prevalence estimates and associated patient socio-demographic features of each ...
The purpose of this study was to further develop the strategy of meet-in-metabolite analysis (MIMA) on our previously reported urinary metabolome data (Shen et al., 2013,Zhang et al., 2014a,Zhang et al., 2014b,Zhang et al., 2014c), and to identify a reasonable biological connection be...