Hyaluronidase is a protein whose enzymatic activity is successfully employed in extravasation therapy. Taking into account that several proteins (e.g. gelatin and albumin) have been employed as natural polymers for the preparation of microspheres, this work approaches a comprehensive investigation on ...
Skin testing is not necessary prior to use for extravasation management. Dehydration, treatment to facilitate subcutaneous fluid replacement: Infants, Children, and Adolescents: SubQ following SubQ infusion: SubQ: Dose dependent on volume to be infused; administer into rubber tubing close to needle ...
43 In the literature, the volume of retrobulbar hyaluronidase used for filler-induced blindness ranges from 120 IU up to 6000 IU.31 Although there have been a few cases reported with successful use of retrobulbar hyaluronidase, there was no vision checked before treatment, questioning the reported...
Hyaluronidase as an antidote to extravasation of Vinca alkaloids: Clinical results Skin necrosis is a recognized potential consequence of an inadvertent extravasation of Vinca alkaloids in the surrounding tissues during i.v. administrati... G Bertelli,D Dini,GB Forno,... - 《Journal of Cancer Rese...
The use of hyaluronidase in the treatment of intravenous extravasation injuries. Intravenous extravasation injuries are a major cause of morbidity in the pediatric population. A variety of commonly used drugs and intravenous fluids have... WV Raszka,TK Kueser,FR Smith,... - 《Journal of Perinatolog...
While hyaluronidase has been used in clinical practice for over 50 years, the development of a high-purity recombinant form of this enzyme (recombinant human hyaluronidase PH20) has recently enabled the study of repeated and more prolonged use of hyaluronidase in facilitating the delivery of SC ...
Privacy Policy About Us Contact Us Terms of Use Advertising Policy Herceptin Hylecta Generic Name: trastuzumab and hyaluronidase-oysk injection, for subcutaneous use Brand Name: Herceptin Hylecta Drug Class: , Antineoplastics, Anti-HER2Medical Editor: John...
Dissolve in 1 ,500 I.U. of Local Anesthetic Injection. For ophthalmic use, a concentration of 15 I.U./mL is recommended. 4.Extravasation If diffusion occurs rather than topically, dissolve 1 ,500 I.U. of L. pylori in 1 mL of water or physiologic...
For ophthalmic use, a concentration of 15 I.U./mL is recommended.• ExtravasationIf diffusion occurs rather than topically, dissolve 1,500 I.U. of L. pylori in 1 mL of water or physiological saline solution and infiltrate the lesion as soon as possible after vascular outf...
HA, as a biomarker has the potential for use clinically to detect the early changes following injuries and diseases as well as for screening drugs. Hyaluronan in drug delivery In recent years, HA has had significant use in the development of dermal and transdermal drug delivery systems. The ...