G. 1958 Role of hyaluronidase in the re-absorption of water in renal tubules; the mechanism of action of the antidiuretic hormone . Nature , 182 : 1218 – 1219 .Ginetzinsky A. Role of hyaluronidase in the re-absorption of water in renal tubules: the mechanism of action of the ...
The mechanism of action of hyaluronidase in this context involves the enzymatic degradation of hyaluronic acid, which allows for better drug penetration and diffusion. Cosmetics: Hyaluronidase is also used in the cosmetics industry. It can be included in skincare products to enhance the penetration ...
Risk summary: Based on its mechanism of action, this drug can cause fetal harm when administered to a pregnant woman. There are no data available on use of this drug in pregnant women to inform a drug-associated risk.Comments:-Verify the pregnancy status of females of reproductive potential ...
G. 1958 Role of hyaluronidase in the re-absorption of water in renal tubules; the mechanism of action of the antidiuretic hormone . Nature , 182 : ... GINETZINSKY,A. G - 《Nature》 被引量: 198发表: 0年 The mechanism of hyaluronidase action 1. 1. The identify of the enzyme site inv...
Based on the mechanism of action and animal data, fetal harm may occur when administered to pregnant women No data available on use in pregnant women to evaluate the drug-associated risk for major birth defects, miscarriage, or adverse maternal or fetal outcomes ...
Mechanism of Action Monoclonal antibody to programmed cell death-1 protein (PD-1); blocks interaction between PD-1 and its ligands, programmed death-ligand 1 (PD-L1) and PD-L2 Product formulation with hyaluronidase, an endoglycosidase, enables subcutaneous administration Nivolumab PD-1 and related ...
Thus, we have identified a path for clinical translation of the cancer resistance mechanism identified in the naked mole rat. Metastasis, the spread of a primary cancer to a distant site, remains the primary cause of cancer mortality, observed in more than 90% of all cancer d eaths1–3...
The mechanism of action of the third group of endo-b-glucuro- nidases resembles that of the eukaryotic or vertebrate hyaluronate 4- glycanohydrolases more closely than that of the bacterial hyaluronate lyases18. Accordingly, a 3D model of LHyal was built based on the recently solved crystal ...
Based on the mechanism of action, DARZALEX FASPRO can cause fetal harm when administered to a pregnant woman. DARZALEX FASPRO may cause depletion of fetal immune cells and decreased bone density. Advise pregnant women of the potential risk to a fetus. Advise females with reproductive potential to...
Potential mechanism of action of intra-articular hyaluronan therapy in osteoarthritis: are the effects molecular weight dependent? Seminars in Arthritis and Rheumatism 32, 10–37. Ghosh, S., Jassal, M., 2002. Use of polysaccharide fibres for modem wound dressings. Indian Journal of Fibre and ...