The meaning of HYALURONIDASE is a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid.
Biochemistry.a mucolytic enzyme found in the testes, in snake venom, and in hemolytic streptococci and certain other bacteria, that decreases the viscosity of the intercellular matrix by breaking down hyaluronic acid. Pharmacology.a commercial form of this substance, used chiefly to promote the diffu...
Most of the hyaluronidases from eukaryotes have both hydrolytic and transglycosidase activity, while those from bacteria operate by β-elimination. HA is prominent whenever rapid cell proliferation and movement occur, particularly during embryogenesis, wound healing, repair and regeneration, and in ...
Many hyaluronidases and hyaluronate lyases produced by eukaryotic cells, bacteria, and bacteriophages have so far been described and annotated, and their ability to cleave hyaluronan has been experimentally proven. These enzymes belong to several carbohydrate-active enzyme families, share very low ...
Hyaluronidase, with the chemical formula C44H63N13O23S2 and CAS registry number 9001-54-1, is an enzyme that catalyzes the degradation of hyaluronic acid, a major component of the extracellular matrix. This enzyme is found in various organisms, including bacteria, insects, and mammals. ...
Hyaluronidases are a family of enzymes that degrade hyaluronic acid (hyaluronan, HA) and widely used in many fields. A hyaluronidase producing bacteria strain was screened from the air. 16S ribosomal DNA (16S rDNA) analysis indicated that the strain belonged to the genus Bacillus, and the strain...
英[haɪəlʊ'rɒnɪdeɪs] 美[ˌhaɪəlʊ'rɒnɪˌdeɪs] 是什么意思 n. 透明质酸酶; 英英释义 hyaluronidase[ ,haiəlju'rɔnideis ] n.an enzyme (trade name Hyazyme) that splits hyaluronic acid and so lowers its viscosity and increases the permeability of ...
Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2]. Properties Articles105 ...
Paradoxically, GAS also produces hyaluronidase (Hyl), an enzyme that cleaves HA. A common assumption is that Hyl digests structurally identical HA in human tissue to promote bacterial spread. We inactivated the gene encoding extracellular hyaluronidase, hylA, in a clinical Hyl(+) isolate. Hyl(+)...
Objective(s): Streptococcus pyogenes produces extracellular hyaluronidase enzyme. This enzyme is directly associated with the spread of the organism during infection. The objective of the present study was to clone and express the nucleotide sequence of the enzyme which is involved in hyaluronidase enzym...