assayoptimizationsubstrate.The current USP XXII assay for hyaluronidase (EC 3.2.1.35, HAse) determines activity indirectly by measuring the amount of undegraded hyaluronic acid (HA) substrate remaining after the enzyme is allowed to react with the HA for 30 min at 37掳C. To be acceptable as a...
The current XXII assay for (EC 3.2.1.35, HAse) determines activity indirectly by measuring the amount of undegraded (HA) substrate remaining after the enzyme is allowed to react with the HA for 30 min at 37 degrees C. To be acceptable as a substrate, the HA must pass a suitability test...
Activity >=300 USP/NF units per mg dry weight. One Unit is based on the change in absorbency (turbidity) at 540 nm of an internal standard assayed concurrently with each lot. Internal standard replaces USP/NF reference no longer available. ...
Description Activity Code Cat. # Size Price Hyaluronidase, Purified Source: Bovine Testes Chromatographically purified. A dialyzed, lyophilized powder. Store at -20°C. … ≥3,000 USP/NF units per mg dry weight Certificate of Analysis HSEP LS005477 5 ku $93.00 LS005475 15 ku $...
This assay may be of benefit for the treatment of metastatic, recurrent, or treatment-refractory unresectable locally advanced breast cancer."Trastuzumab for Breast CancerIn a large, randomized controlled trial, trastuzumab improved response rates to chemotherapy by 53 % in women with metastatic breast...
In DARZALEX FASPRO-treated patients with persistent very good partial response, where daratumumab interference is suspected, consider using a FDA-approved daratumumab-specific IFE assay to distinguish daratumumab from any remaining endogenous M protein in the patient’s serum, to facilitate determination ...
as potential inhibitors of huRPA32’s DNA-binding activity, offering promising avenues for cancer therapy. Overall, our findings position the stem extract ofN. mirandaas a promising source of natural compounds for anticancer therapeutics and anti-skin-aging treatments, warranting further investigation in...