Disordered Nanostructure in Huntingtin Interacting Protein K Acts as a Stabilizing Switch To Prevent Protein Aggregation Disordered Nanostructure in Huntingtin Interacting Protein K Acts as a Stabilizing Switch To Prevent Protein Aggregation DK Ghosh,A Roy,A Ranjan - 《Biochemistry》...
Raychaudhuri S, Majumder P, Sarkar S, Giri K, Mukhopadhyay D, et al. (2008) Huntingtin interacting protein HYPK is intrinsically unstructured. Proteins 71: 1686-1698.Raychaudhuri, S. et al. Huntingtin interacting protein HYPK is intrinsically unstructured. Proteins 71, 1686-1698 (2008)....
Actin Binding by Hip1 (Huntingtin-interacting Protein 1) and Hip1R (Hip1-related Protein) Is Regulated by Clathrin Light Chain The huntingtin-interacting protein family members (Hip1 and Hip1R in mammals and Sla2p in yeast) link clathrin-mediated membrane traffic to actin cytoskele... JD Wilb...
(2008) Huntingtin interacting protein HYPK is intrinsically unstructured. Proteins 71: 1686-1698.Raychaudhuri, S. et al. Huntingtin interacting protein HYPK is intrinsically unstructured. Proteins 71, 1686-1698 (2008).Raychaudhuri S, Majumder P, Sarkar S, Giri K, Mukhopadhyay D, et al. (2008) ...
Huntingtin-interacting protein 1 (HIP1) interacts with huntingtin, the protein whose gene is mutated in Huntington's disease. In addition, a fusion between HIP1 and platelet-derived growth factor beta receptor causes chronic myelomonocytic leukemia. The HIP1 proteins, including HIP1 and HIP1-relate...
Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase. Oncogene 23 : 9230-9237.Ducker, C.E., Stettler, E.M., French, K.J., Upson, J.J., and Smith, C.D. (2004). Huntingtin interacting protein 14 is an oncogenic human protein: Palmitoyl acyltransferase...
Fmrp, a known regulator of ribosome stalling, is upregulated in HD, but its depletion has no discernible effect on protein synthesis or ribosome stalling in HD cells. We found interactions of ribosomal proteins and translating ribosomes with mHtt. High-resolution global ribosome footprint profiling...
The huntingtin protein in unaffected individuals can have a polyglutamine tract with up to 35 repeats, whereas the disease manifests when the expansion reaches 40 or more repeats (1). The age of onset of symptoms is related to the number of glutamines, with longer stretches leading to earlier...
Kim S., Kim K.T. Therapeutic approaches for inhibition of protein aggregation in Huntington's disease Exp. Neurobiol, 23 (2014), pp. 36-44 10.5607/en.2014.23.1.36 24737938 CrossrefGoogle Scholar 11 Vashishtha M., Ng C.W., Yildirim F., Gipson T.A., Kratter I.H., Bodai L., Song ...
(i–k) Time-course analyses of the levels of Tau-ΔC-GFP protein expressed from stably transfected Dox-inducible HeLa cell line. Degradation of Tau-ΔC-GFP was significantly delayed by (i) autophagy inhibitor 3-MA or (j) by siRNA-mediated knockdown of ATG7, whereas (k) proteasome ...