DataSheetSDSCOAHPLCHNMRLCMS产品操作手册 产品介绍 生物活性 产品描述 SB-200646 is a selective and potent antagonist of 5-HT2B/5-HT2C receptor 靶点活性 5-HT2B receptor:7.5 (pKi) , 5-HT2A receptor:5.2 (pKi), 5-HT2C receptor:6.9 (pKi)
DataSheetSDSCOAHPLCHNMR产品操作手册 产品介绍 生物活性 产品描述 Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy. 别名多拉司琼, MDL-73147
DataSheet SDS COA HPLC LCMS HNMR产品操作手册 产品介绍 生物活性 产品描述 Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects. 靶点活性 5-HT3 receptor:0.33 nM 体外活性 在初级皮层神经元细胞中,Bemesetron(1 μM)显著阻断H2O2诱导的caspase-3...
DataSheetSDSCOAHNMRHPLC产品操作手册 产品介绍 生物活性 产品描述 Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. 靶点活性 5-HT3 receptor (cell-free assay):0.81 μM 体内活性 老年大鼠中,观察到总清除率和中心区室的分布体积有所下降。Lerisetron的自由(未...
DataSheetSDS产品操作手册 产品介绍 生物活性 产品描述 Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic. 靶点活性 5-HT4 receptor:0.14 μM (EC50) ...
DataSheet SDS COA HPLC HNMR LCMS产品操作手册 产品介绍 生物活性 产品描述 Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of suici...
DataSheetSDS产品操作手册 产品介绍 生物活性 产品描述 Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic. It recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin leads to apoptosis. Neocarzinostatin has potential for EpCAM-positive cance...
DataSheetSDSCOALCMSHPLCHNMR产品操作手册 产品介绍 生物活性 产品描述 Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Ramos...
DataSheet SDS COA HPLC LCMS HNMR产品操作手册 产品介绍 生物活性 产品描述 Asenapine Maleate (Org 5222 maleate) is a second generation (atypical) antipsychotic agent that is taken sublingually and used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disorder. ...
DataSheet SDS产品操作手册 产品介绍 生物活性 产品描述 L-694,247 is a selective 5-HT receptor agonist with affinity for 5-HT1D, 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT1E receptors, and can be used to study neurological diseases. 靶点活性 5-HTIB:9.1 (pIC50), [125I]-GTI-5-HTID:10.0...