A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis Source: Nature Communications Targeting the dynamic HSP90 complex in cancer Source: Nature Reviews Cancer Mitochondrial-derived vesicles: Gatekeepers of mitochondrial response to oxidative stress ...
2. **"A monoclonal antibody targeting HSP90AA1 inhibits tumor growth in HER2-positive breast cancer models"** - **作者**: Smith SJ, et al. - **摘要**: 研究开发了一种靶向HSP90AA1的单克隆抗体,证明其可通过降解HER2蛋白抑制乳腺癌细胞增殖和移植瘤生长,为靶向治疗提供新策略。 3. **"Structural ...
[38] previously reported that the miRNA was downregulated in breast cancer clinical samples and cell lines, and that its ectopic expression in breast cancer cells impaired proliferation, invasion, and migration as well as tumorigenesis in a xenograft mouse model. Conversely, Yang et al. [42] ...