Huntington's disease is a degenerative, hereditary, genetic illness similar to Parkinson's and it affects one in 10,000 in the population. Not only does it destroy the person - mind and body - but it destroys entire families as well. West Belfast journalist SHANE McKAY writes of the havoc...
obsessive compulsive disorder, and Tourette's syndrome. In this study, at least one of the genes that the researchers discovered was overexpressed in the striosomes of Huntington's brains is also linked to autism.
The discovery of a polymorphic DNA marker for Huntington's Disease (HD) in 1983, and the specific gene responsible in 1993, led to predictive testing programmes out of which came research into whether or not cognitive impairment was present presymptomatically in those at risk for HD. The result...
Huntington disease: How many repeats does it take? 来自 NCBI 喜欢 0 阅读量: 8 作者: Hogarth,P. 摘要: Comment on Neurology. 2013 May 28;80(22):2022-7. 关键词: Humans Huntington Disease Nerve Tissue Proteins Phenotype Trinucleotide Repeat Expansion Male DOI: 10.1212/WNL.0b013e3182984b31...
To evaluate the potential for refinement, as well as its implementation in research, we analysed papers on murine models of Huntington's disease (HD) published between 1999 and 2009 (n = 233). Each study was classified according to a four-level severity scale, in terms of the disease stage...
Understanding quality of life (QoL) is important in diseases for which there is no cure to date, such as Huntington’s disease (HD). A deeper level of understanding is, however, compromised by the lack of studies examining QoL from the perspectives of HD gene expansion carriers (HDGECs). ...
A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites—long finger-like extensions that make connections all through the brain—bec...
Huntington’s disease Sickle cell anemia Autism Alzheimer’s disease agitation Neuropathies Cachexia and wasting syndrome In a doctor’s professional judgment, any chronic, debilitating, or other medical condition, including hepatitis C In many ways, Missouri residents are fortunate. There were a pair ...
Sure, pruning roses can be a chore, but your efforts will be rewarded by a healthier, well-shaped plant that blooms abundantly and lives longer. Pruning out dead or diseased canes helps to increase airflow and sun penetration around living canes, which helps to ward off disease and encourage...
a simple goal-directed sensorimotor behavior. The findings add a missing piece in the puzzle of the brain, contributing to our fundamental understanding of a brain area that is intimately involved in neurodegenerative disorders like Parkinson's and Huntington's disease. The work is published in...