(redirected fromVariant Allele Frequency) Category filter: AcronymDefinition VAFVariant Allele Frequency(pathology) VAFVirginia Association of Fairs VAFVisual Studio Analyzer Filter VAFVoluntary Action Fund(UK) VAFVisa Application Form(various nations) ...
Based on the table it is possible to calculate row and column wise parameters, PPV and NVP, and sensitivity and specificity, respectively. These parameters are useful, but are not based on all the information in the table. Accuracy is a measure that is calculated based on all the four ...
Genes known to be upregulated during mesothelioma development, such asOsteopontin(Spp1) andmesothelin(Msln), were increased validating our approach (Fig.4a). As expected the expression ofNf2andBap1, tumor suppressors frequently mutated in mesothelioma [24,25,26,27] were significantly decreased during...
The fact that a gene that reduces population fitness can spread is the basis for the strategy of population suppression. In this simple case of a dominant functional gene it is straightforward to calculate the genetic load the spread of the DEG places on the population [20]. At equilibrium, ...
This was demonstrated by the simultaneous detection of the mutation underlying Miller syndrome by WGS of a family consisting of two affected siblings and their parents with the added bonus of being able to calculate a human intergenerational mutation rate of approximately 1.1 × 10-8 per position ...