HLA-DQ2.2 can only bind a subset of the gluten peptides that can bind to HLA-DQ2.5. This difference is explained by the fact that a proline at position 3 in peptides has an adverse effect on peptide binding
HLA-DQ2.2 can only bind a subset of the gluten peptides that can bind to HLA-DQ2.5. This difference is explained by the fact that a proline at position 3 in peptides has an adverse effect on peptide binding