Download: Download full-size image Fig. 1. Proposed metabolism of acrylamide.Adapted from Sumner et al., 1992, Sumner et al., 2003. The hemoglobin adducts (Hb) with acrylamide and glycidamide in blood and the mercapturic acids metabolites of acrylamide and glycidamide in the urine can be ...
An organic compound known as 5-hydroxymethylfurfural (HMF) is formed from reducing sugars in honey and various processed foods in acidic environments when they are heated through the Maillard reaction. In addition to processing, storage conditions affect
sv_vcf Full path and filename for the SV VCF, otherwill will use the Purple SV VCF (ie SAMPLE_ID.purple.vcf.gz) in the configured Purple directory proximity_distance minimum distance to cluster SVs (default = 5000) chaining_sv_limit threshold for # SVs in clusters to skip chaining routin...
For these purposes, PURPLE provides full support and integration with the structural variant caller GRIDSS. GRIDSS can be run directly on tumor and reference BAMs. Alternatively a lightweight version of GRIDSS can be used to re-analyse a set of variant calls and provide additional filtering and ...