结论HLA-A*02等位基因在中国南、北汉族人群中的分布呈现高度杂合和遗传多样性并具有显著性差异,HLA-A*020101、A*0203和A*0207可作为人类学研究中区分中国南北汉族人群的遗传标志。 Abstract:ObjectiveTo investigate the distributions of HLA-A∗02 alleles in Han populations and compare their difference between ...
An assay positive control is provided (Cat#280301) that can be diluted to a high, medium, and low concentration. Signal intensity can be correlated to affinity of the peptide. What is the peptide exchange technology and what's the advantage of using it? Flex-T™ MHC monomers are ...
A 0 2 was positive in 691 individuals wi山 0 . 301 of low-resolution f r equency .E ight dif f erent HL A— A * 02 alleles, A * 020 I , A * 0203, A * 0205 , A * 0206 . A * 0207 , A * 0 210 . A * 02 11 an d A * 02 90 , were identif i ed in Chi nes...
The positive rates of HLA-A*02 was significantly higher in cancer patients than in healthy controls (P=0.004,OR=2.432,95% CI=1.314-4.500),which were 68.75% and 47.50%,respectively.The gene frequency of HLA-A*02 was significantly higher in cancer patients than in healthy controls(P0.05),...
(Hubeiprovince).Methods:PCR-SSOPandPCR-SBTwereusedtoanalyzethehighresolutiontypingHLA-Ageneof1364volunteersinHubeiprovince.Results:AmongthetestedHLA-Ageneof1364volunteers,A*02waspositivein691individualswith0.301oflow-resolutionfrequency.EightdifferentHLA-A*02alleles,A*0201,A*0203,A*0205,A*0206,A*0207,A...
gondii seronegative and seropositive individuals were evaluated by ELISpot. Peptides with higher IFN-γ induction were evaluated to identify cytotoxic response in CD8+ T cells (CD107a). In silico analysis identified 36 peptides from T. gondii proteins with predicted affinity to HLA-A*02, A*24...
We eval- uated the sensitivity and positive predictive value (PPV) of IL28B and the two HLA alleles described above (HLA-A*02:01 and DRB1*11:01) with HCV clearance. As shown in Table S5, after adjusting for age and gen- der, the sensitivity of IL28B on HCV clearance was ...
Evolutionary analysis of classical HLA class I and II genes suggests that recent positive selection acted on DPB1*04:01 in Japanese population. PloS one 7, e46806, DOI:10.1371/ journal.pone.0046806 (2012). 18. Nakaji, S., Ueta, M., Sotozono, C., Inatomi, T. & Kinoshita, S. [...
Novel genetic loci associated HLA-B*08:01 positive myasthenia gravis OBJECTIVE: To identify potential causative markers involved in the development of early-onset myasthenia gravis (EOMG) in the MHC and non-MHC regions that ... J Varade,N Wang,CK Lim,... - 《Journal of Autoimmunity...
展开 关键词: Animals Mice, Inbred C57BL Humans Mice CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes HLA-A1 Antigen HLA-B8 Antigen HLA-B27 Antigen HLA-C Antigens DOI: 10.4049/jimmunol.1300483 被引量: 41 年份: 2013 收藏 引用 批量引用 报错 分享 全部...