We tested the hypothesis that IPC attenuates post-ischemic neuronal death in the gerbil hippocampal CA1 region (CA1) throughout hypoxia inducible factor-1 alpha (HIF-1 alpha) and its associated factors such as vascular endothelial growth factor (VEGF) and nuclear factor-kappa B (NF-kappa B)....
In conclusion, reduced proliferation and increased apoptosis in A549 lung cancer cells was associated with inhibition of the PI3K/AKT/HIF-1 alpha/ and NF-kappa B/COX-2 signaling pathways, which implicates genistein as a potential chemotherapeutic agent for the treatment of lung cancer....
nf-kappa bstresscyclophosphamide, doxorubicin, prednisone, and vincristinehypoxia inducible factor 1, alpha subunitmitogen-activated protein kinase p38Obesity is marked by metabolic inflammation and by metabolic impairment caused by increased endotoxin, free fatty acids, and vascular endothelial growth factor...