HIF-1αosteogenesisA successful clinical outcome for implanted tissue-engineered bone is dependent on the establishment of a functional vascular network. Gene-enhanced tissue engineering represents a promising approach for vascularization and osteogenesis. In the present study, we tested the angiogenesis ...
Several case-control articles stressed the connection between lung cancer danger and HIF-1[alpha] gene polymorphism, but the conclusions were conflicting. Thus, this meta-analysis was carried out to assess the connection between HIF-1[alpha] gene polymorphisms (rs11549467, rs11549465, and rs2057...
The effects of HIF-1alpha on gene expression profiles of NCI-H446 human small cell lung cancer cells. J Exp Clin Cancer Res 2009;28:150.The effects of HIF-1 alpha on gene expression profiles of NCI-H446 human small cell lung cancer cells. Wan J,Ma J,Mei J,et al. Journal of ...
Sun X,Vale M,Jiang X, et al.Antisense HIF-1alpha prevents acquiredtumor resistance to angiostatin gene therapy. Cancer Gene Therapy . 2010Sun X Vale M Jiang X Gupta R Krissansen GW . Antisense HIF-1alpha prevents acquired tumor resistance to angiostatin gene therapy. [J]. 2010,8(8) ....
Here, we used RNA interference to determine the contribution of HIF-1alpha vs. HIF-2alpha to the hypoxic gene induction. Surprisingly, most genes tested were responsive only to the HIF-1alpha siRNA, showing no effect by HIF-2alpha knock-down. The same was found for the activation of ...
VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma. Med Oncol. 2014; 31:840. [PubMed: 24446253]Lessi F,Mazzanti C M,Tomei S,et al.VHL and HIF-1alpha:gene variations and prognosis in earlystage clear cell renal cell carcinoma[J].Med Oncol,...
5261. The intestinal cancer cell strain expressing the HIF-1 alpha gene efficiently can be used in the fields such as research of an intestinal cancer mechanism and sifting of cancer treatment medicine, and provides a quite valuable tool for the basic and clinic research.周利红...
HIF-1[alpha] or VEGF gene expression level was independent of age, clinical stage and histological subtype besides grade of tumor. There was no relationship between HIF-1[alpha] or VEGF gene expression level and IMD in all carcinomas (R=0.118 and 0.224, respectively). In addition, a weak ...
Kakinuma Y, Katare RG, Arikawa M, Muramoto K, Yamasaki F, Sato T: A HIF-1alpha-related gene involved in cell protection from hypoxia by suppression of mitochondrial function. FEBS Lett 2008; 582: 332-340.Kakinuma Y, Katare RG, Arikawa M, et al. A HIF-1alpha-related gene involved ...
HIF1-alphaVEGFIDH1mutationGoals Glioblastoma multiforme (GBM) is the most common form of primary brain tumors. Although mutations in isocitrate dehydrogenase-1 (IDH1) have been identified in a number of cancers, their role in tumor development has not been fully elucidated. In this study, we ...